Wal-yan Respiratory Research Centre
WAERP
Team
Airway Epithelial Research projects
Reports and Findings
Current and novel therapies for management of Acinetobacter baumannii-associated pneumonia
Acinetobacter baumannii is a common pathogen associated with hospital-acquired pneumonia showing increased resistance to carbapenem and colistin antibiotics nowadays. Infections with A. baumannii cause high patient fatalities due to their capability to evade current antimicrobial therapies, emphasizing the urgency of developing viable therapeutics to treat A. baumannii-associated pneumonia.
Published research Airway Epithelial Research Subsite: WalyanThe respiratory health effects of acute in vivo diesel and biodiesel exhaust in a mouse model
Biodiesel, a renewable diesel fuel that can be created from almost any natural fat or oil, is promoted as a greener and healthier alternative to commercial mineral diesel without the supporting experimental data to back these claims. The aim of this research was to assess the health effects of acute exposure to two types of biodiesel exhaust, or mineral diesel exhaust or air as a control in mice.
Published research Airway Epithelial Research Respiratory Environmental Health Subsite: Walyan Biodiesel studies Lung functionAntenatal creatine supplementation reduces persistent fetal lung inflammation and oxidative stress in an ovine model of chorioamnionitis
Chorioamnionitis is a common antecedent of preterm birth and induces inflammation and oxidative stress in the fetal lungs. Reducing inflammation and oxidative stress in the fetal lungs may improve respiratory outcomes in preterm infants. Creatine is an organic acid with known anti-inflammatory and antioxidant properties.
Published research Early Childhood Development Nutrition Airway Epithelial Research Chronobiology Subsite: Walyan Lung functionExploring the Complexity of the Human Respiratory Virome through an In Silico Analysis of Shotgun Metagenomic Data Retrieved from Public Repositories
Respiratory viruses significantly impact global morbidity and mortality, causing more disease in humans than any other infectious agent. Beyond pathogens, various viruses and bacteria colonize the respiratory tract without causing disease, potentially influencing respiratory diseases’ pathogenesis.
Published research Airway Epithelial Research P4 Respiratory Health for Kids Subsite: Walyan Respiratory viral infections