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        1-10 of 42 results for 'Peter Le souef'

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        Research

        Polymorphisms in key innate immune genes and their effects on measles vaccine responses and vaccine failure in children from Mozambique

        Despite an effective vaccine, measles remains a major health problem globally, particularly in developing countries. More than 30% of children show primary... ...

        Research

        Acute infection and long term follow-up of people with HIV

        Investigators: Peter Le Souef Project description There have been almost no studies of the first illness caused by HIV infection. We have recruited ...

        Research

        Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children

        Malaria is a deadly disease caused by Plasmodium spp. Several blood phenotypes have been associated with malarial resistance, which suggests a genetic component to immune protection. ...

        Research

        Defining Age-specific Relationships of Respiratory Syncytial Virus and Rhinovirus Species in Hospitalized Children With Acute Wheeze

        Acute wheezing is one of the most common hospital presentations for young children. Respiratory syncytial virus (RSV) and rhinovirus (RV) species A, B and the more recently described species C are implicated in the majority of these presentations. However, the relative importance and age-specificities of these viruses have not been defined. ...

        Research

        Increased nasal Streptococcus pneumoniae presence in Western environment associated with allergic conditions in Chinese immigrants

        Chinese immigrants living in Australia experience increased allergic conditions: asthma, eczema, hay fever and wheeze. Recently we reported diminished innate cytokine responses in long-term immigrants, potentially increasing their pathogenic viral load and microbial carriage. We hypothesise that a Western environment changes the nasal microbiome profile, and this altered profile may be associated with the development of allergic conditions. In this cross-sectional study, we aimed to examine the loading of viral and microbial respiratory pathogens in the upper airway. ...

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        Research to help identify which children will develop asthma and to design more specific asthma treatments supported by Federal Government funding

        Research focussed on identifying which children will develop asthma, and developing more specific asthma treatments, has been supported by the National Health and Medical Research Council’s (NHMRC) Ideas Grants announced by the Federal Government on 14 December 2022. ...

        People

        Ingrid Laing

        Honorary Research Fellow ...

        6319 1828 Email me
        Research

        Future Child Health

        Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate ...

        Children’s Respiratory Science

        The Children’s Respiratory Science group’s research has an emphasis on mechanisms of respiratory health in children including those that predict and underpin acute viral respiratory infections in children. ...

        Research

        Personal network inference unveils heterogeneous immune response patterns to viral infection in children with acute wheezing

        Human rhinovirus (RV)-induced exacerbations of asthma and wheeze are a major cause of emergency room presentations and hospital admissions among children. Previous studies have shown that immune response patterns during these exacerbations are heterogeneous and are characterized by the presence or absence of robust interferon responses. ...

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