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        Research

        Adiposity associated DNA methylation signatures in adolescents are related to leptin and perinatal factors

        Epigenetics links perinatal influences with later obesity. We identifed differentially methylated CpG (dmCpG) loci measured at 17 years associated with concurrent adiposity measures and examined whether these were associated with hsCRP, adipokines, and early life environmental factors. Genome-wide DNA methylation from 1192 Raine Study participants at 17 years, identified 29 dmCpGs associated with body mass index, 10 with waist circumference and 9 with subcutaneous fat thickness. ...

        Research

        The collective impact of rare diseases in Western Australia: An estimate using a population-based cohort

        This cohort study provides new evidence of a disparity between the proportion of the population with rare diseases and their combined health-system costs ...

        Research

        Short report: Care for children and adolescents with diabetes in Australia and New Zealand: Have we achieved the defined goals?

        In 2010, the Australasian Paediatric Endocrinology Group formed a national Children's Diabetes Network that represented clinical teams managing over 95% of... ...

        Research

        Cohort description: Measures of early-life behaviour and later psychopathology in the LifeCycle Project - EU Child Cohort Network

        The EU LifeCycle Project was launched in 2017 to combine, harmonise, and analyse data from more than 250,000 participants across Europe and Australia, involving cohorts participating in the EU-funded LifeCycle Project. The purpose of this cohort description is to provide a detailed overview over the major measures within mental health domains that are available in 17 European and Australian cohorts participating in the LifeCycle Project. ...

        Research

        Associations between Prenatal Exposure to Phthalates and Features of the Metabolic Syndrome in Males from Childhood into Adulthood

        Phthalate metabolites are detectable within the majority of the population. Evidence suggests that a prenatal exposure to phthalates may be associated with the subsequent risks of obesity and elevated blood pressure. We hypothesised that a prenatal exposure to phthalates would lead to an increase in adverse cardiometabolic parameters through childhood and adulthood. ...

        Research

        The mental health and wellbeing of adolescents on remand in Australia

        To compare the nature & prevalence of mental health problems, prevalence of suicidal ideation & behaviour, & health-related quality of life of 13-17-year-olds.. ...

        Research

        Self-citation in American Physiological Society Journals

        This study investigates the incidence of self-citation (authors citing their own work) for scholarly articles in ten journals published by the American... ...

        Research

        Method of bacterial killing differentially affects the human innate immune response to Staphylococcus epidermidis

        In vitro investigations of human innate immune responses to extracellular bacteria commonly utilise killed preparations in preference to live... ...

        Research

        The impact of pandemic A(H1N1)pdm09 influenza and vaccine-associated adverse events on parental attitudes and influenza vaccine uptake in young children

        This paper reports on the shift in parental attitude to vaccination after 2010, due to an unprecedented increase in febrile reactions in children receiving... ...

        Research

        Joint attention and parent-child book reading

        Good language development is an integral component of school readiness and academic achievement. ...

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