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        Research

        Home-based multidisciplinary interventions on skin adverse reactions in EGFR-TKI-treated patients with lung cancer: a protocol for a randomised controlled trial

        Here, we provide a feasible, well-designed protocol of a randomised controlled trial for the assessment of the effects of a home-based multidisciplinary intervention on the severity of skin adverse drug reactions and health-related indicators in patients with non-small cell lung cancer (NSCLC) under epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) therapy. ...

        Research

        Prevalence and predictors of vitamin D deficiency in a nationally representative sample of Australian adolescents and young adults

        Vitamin D deficiency is a public health concern worldwide. Maintaining vitamin D sufficiency during growth periods is essential. We aimed to determine the prevalence and predictors of vitamin D deficiency in Australian adolescents and young adults. ...

        Research

        Genomic analyses in Cornelia de Lange Syndrome and related diagnoses: Novel candidate genes, genotype–phenotype correlations and common mechanisms

        Cornelia de Lange Syndrome (CdLS) is a rare, dominantly inherited multisystem developmental disorder characterized by highly variable manifestations of growth and developmental delays, upper limb involvement, hypertrichosis, cardiac, gastrointestinal, craniofacial, and other systemic features. ...

        Research

        Defining the role of common variation in the genomic and biological architecture of adult human height

        Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability... ...

        Research

        Net benefit of smaller human populations to environmental integrity and individual health and wellbeing

        The global human population is still growing such that our collective enterprise is driving environmental catastrophe. Despite a decline in average population growth rate, we are still experiencing the highest annual increase of global human population size in the history of our species-averaging an additional 84 million people per year since 1990. ...

        Research

        Techniques and Processes Involved in Nanoencapsulation of Omega-3, -6, and -9 Fatty Acids

        Omega fatty acids are essential for young children’s growth and development. They also have essential functions in cell receptors of membranes and regulation of hormones synthesis. Essential fatty acids such as omega-3 and -6 can only be obtained through food mainly fish and other seafood and to a lesser extent through nuts, seeds, and plant oils. ...

        Research

        Revisiting the inoculum effect for Streptococcus pyogenes with a hollow fibre infection model

        Severe, invasive Streptococcus pyogenes (Strep A) infections result in greater than 500,000 deaths annually. First line treatment for such infections is benzylpenicillin, often with the addition of clindamycin, but treatment failure can occur with this regimen. This failure has been partially attributed to the inoculum effect, which presents as reduced antibiotic susceptibility during high bacterial density and plateau-phase growth. ...

        Research

        Joint developmental trajectories of internalizing and externalizing problems from mid-childhood to late adolescence and childhood risk factors: Findings from a prospective pre-birth cohort

        There is limited evidence on heterogenous co-developmental trajectories of internalizing and externalizing problems from childhood to adolescence and predictors of these joint trajectories. We utilized longitudinal data from Raine Study participants to identify these joint trajectories from 5 to 17 years using parallel-process latent class growth analysis and analyze childhood individual and family risk factors predicting these joint trajectories using multinomial logistic regression. ...

        News & Events

        Baby's Social and Developmental Milestones

        Paediatrician Dr Lana Bell's tips on identifying baby developmental milestones ...

        Research

        Ndrg1 in development and maintenance of the myelin sheath

        CMT4D disease is a severe autosomal recessive demyelinating neuropathy with extensive axonal loss leading to early disability, caused by mutations... ...

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