Although debate surrounding the mechanism or mechanisms governing this causal pathway remains intense, demonstration of the capacity of pretreatment... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• May 2015

We sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• August 2017

The aim of this study was to explore associations between severe respiratory infections and atopy in early childhood with persisting wheeze and asthma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• April 2012

The airway epithelium forms a highly regulated physical barrier that normally prevents invasion of inhaled pathogens and allergens from the airway lumen. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• July 2011

Vitamin D has been linked in some studies with atopy- and asthma-associated phenotypes in children with established disease,but its role in disease inception... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• May 2011

The hallmark of atopic asthma is transient airways hyperresponsiveness (AHR) preceded by aeroallergen-induced Th-cell activation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

Anti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• January 2010

The airway epithelium of children with asthma is characterized by aberrant repair that may be therapeutically modifiable. The development of epithelial-targeting therapeutics that enhance airway repair could provide a novel treatment avenue for childhood asthma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

To introduce a disease prognosis framework enabled by a robust classification scheme derived from patient-specific transcriptomic response to stimulation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

Research focussed on identifying which children will develop asthma, and developing more specific asthma treatments, has been supported by the National Health and Medical Research Council’s (NHMRC) Ideas Grants announced by the Federal Government on 14 December 2022. ...

• Wal-yan Respiratory Research Centre
• News & events
• 2023
• January