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        Research

        Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner

        Chemotherapy is included in treatment regimens for many solid cancers, but when administered as a single agent it is rarely curative. The addition of immune checkpoint therapy to standard chemotherapy regimens has improved response rates and increased survival in some cancers. However, most patients do not respond to treatment and immune checkpoint therapy can cause severe side effects. Therefore, there is a need for alternative immunomodulatory drugs that enhance chemotherapy. ...

        Research

        Post-surgery financial toxicity and its influencing factors in colorectal cancer care: A cross-sectional study

        This study aimed to investigate the influence factors of financial toxicity experienced by colorectal cancer patients after surgery. The results will provide deep insights for developing effective intervention strategies to address this common issue of colorectal cancer care. ...

        Research

        Identification of fatty acid amide hydrolase as a metastasis suppressor in breast cancer

        Clinical management of breast cancer (BC) metastasis remains an unmet need as it accounts for 90% of BC-associated mortality. Although the luminal subtype, which represents >70% of BC cases, is generally associated with a favorable outcome, it is susceptible to metastatic relapse as late as 15 years after treatment discontinuation. ...

        Research

        Does Exposure to Asbestos Cause Ovarian Cancer? A Systematic Literature Review and Meta-analysis

        The asbestos and ovarian cancer relationship is not well understood because of small numbers of women exposed to asbestos, small numbers of cases... ...

        News & Events

        Raine Foundation grants support exciting projects in childhood cancer and newborn infections

        Two Telethon Kids Institute researchers have been awarded prestigious grants from the Raine Medical Research Foundation for projects in childhood cancer and newborn infection control. ...

        News & Events

        Cheers as Beau’s curls cut to fund cancer fight

        A brave young man stepped up to the plate on Friday to do his part in the battle against cancer. ...

        News & Events

        Telethon Kids researchers share in $1.75m ACRF grant for cancer research

        Three Telethon Kids researchers are collaborating on a cancer research project that has been awarded a $1.75mill grant by the Australian Cancer Research Fund. ...

        Research

        Women Diagnosed with Ovarian Cancer: Patient and Carer Experiences and Perspectives

        By directly engaging with women diagnosed with ovarian cancer, this study aimed to explore and identify their view of the health symptoms and outcomes that matter most to them as they traverse their disease pathway. ...

        Research

        Cochrane corner: platinum-induced hearing loss after treatment for childhood cancer

        This systematic review shows that children treated with platinum analogues are at risk of developing hearing loss ...

        Research

        Parents' Experiences of Childhood Cancer During the COVID-19 Pandemic: An Australian Perspective

        COVID-19 has had far-reaching impacts including changes in work, travel, social structures, education, and healthcare. This study aimed to explore the experiences of parents of children receiving treatment for cancer during the COVID-19 pandemic. ...

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