Vaccine prevention of GAS infections and their immunological complications has been a goal of researchers for decades. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• April 2013

Group A Streptococcus (GAS) M protein is an important virulence factor and potential vaccine antigen, and constitutes the basis for strain typing (emm-typing). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• May 2013

Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@ ...

• 1. Telethon Kids Institute
• Projects

Group A streptococcal (GAS) infections can trigger an immune-mediated response resulting in acute rheumatic fever. The role of social and environmental risk factors for GAS pharyngitis and skin infections are not well understood. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

Dr Dylan Barth collecting a dried blood sample while Slade completes the SToP Trial jigsaw puzzle It takes about five minutes to boil water and brew ...

• 1. Telethon Kids Institute
• Our research
• Research Impact
• 2021
• In the pipeline

This paper is a report on progress towards a joint Australian and New Zealand vaccination program for Group A Streptococcus bacteria, which causes serious... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• May 2014

The median number of presentations per child in the first year of life was 21 with multiple reasons for presentation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• March 2013

Indigenous children and young peoples live with an inequitable burden of acute rheumatic fever and rheumatic heart disease. In this Review, we focus on the epidemiological burden and lived experience of these conditions for Indigenous young peoples in Australia, New Zealand, and Canada. We outline the direct and indirect drivers of rheumatic heart disease risk and their mitigation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Rheumatic heart disease (RHD) remains the leading cause of cardiac-related deaths and disability in children and young adults worldwide. In The Gambia, the RHD burden is thought to be high although no data are available and no control programme is yet implemented. We conducted a pilot study to generate baseline data on the clinical and valvular characteristics of RHD patients at first presentation, adherence to penicillin prophylaxis and the evolution of lesions over time. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

We reflect on the lessons learned from a recent genome‐wide association study of rheumatic heart disease with Aboriginal Australian participants ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020