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        Research

        Protective benefit of predominant breastfeeding against otitis media may be limited to early childhood: results from a prospective birth cohort study

        Our findings are in line with a number of epidemiological studies which show a positive association between breastfeeding and OM in early childhood ...

        Research

        Children with otitis media mount a pneumococcal serotype specific serum IgG and IgA response comparable to healthy controls after pneumococcal conjugate vaccination

        We investigated the suggestion that otitis-prone children have an impaired antibody response in the context of pneumococcal vaccination. ...

        Research

        Genetic and functional evidence for a role for SLC11A1 in susceptibility to otitis media in early childhood in a Western Australian population

        Otitis media (OM) is a common disease in early childhood characterised by inflammation of the middle ear. ...

        Research

        Immunogenicity, otitis media, hearing impairment, and nasopharyngeal carriage 6-months after 13-valent or ten-valent booster pneumococcal conjugate vaccines, stratified by mixed priming schedules: PREVIX_COMBO and PREVIX_BOOST randomised controlled trials

        Australian First Nations children are at very high risk of early, recurrent, and persistent bacterial otitis media and respiratory tract infection. With the PREVIX randomised controlled trials, we aimed to evaluate the immunogenicity of novel pneumococcal conjugate vaccine (PCV) schedules. ...

        Research

        Safety, tolerability, and effect of a single aural dose of Dornase alfa at the time of ventilation tube surgery for otitis media: A Phase 1b double randomized control trial

        One third of children require repeat ventilation tube insertion (VTI) for otitis media. Disease recurrence is associated with persistent middle ear bacterial biofilms. With demonstration that Dornase alfa (a DNase) disrupts middle ear effusion biofilms ex vivo, we identified potential for this as an anti-biofilm therapy to prevent repeat VTI. First, safety and tolerability needed to be measured. ...

        Research

        Healthy Ears Clinical Trial: A telehealth-facilitated randomised-controlled trial utilising a health promotion intervention to resolve otitis media with effusion for children won specialist Ear, Nose and Throat (ENT) waiting lists

        Chris Peter Valerie Lea-Ann Ruth Jaimee Melinda Charlie Elke Tamara Robyn Brennan-Jones Richmond Swift Kirkham Thornton Rich Edmunds McLeod Seppanen ...

        Research

        ATOMIC Ears: A Phase IIB randomised controlled trial to assess safety, tolerability and acceptability of a 5-day Dornase alfa treatment as an adjunct therapy to ventilation tube insertion for otitis media in children

        Chris Jennifer Lea-Ann Peter Ruth Brennan-Jones Kent Kirkham Richmond Thornton C J LK PC RT PhD RN PhD MBBS MRCP(UK) FRACP PhD Head, Ear Health ...

        News & Events

        MEDIA ENQUIRIES What's happening Video Centre More news Please direct general enquiries to our reception on (08) 9489 7777. Please direct media ...

        Diabetes news and events

        A listing of all Diabetes-related news from the Children's Diabetes Centre, including latest stories, media releases, and interviews. ...

        News & Events

        Brain & Behaviour community forum

        We invite you to join us for a community forum on the future of research in our Brain & Behaviour Research Focus Area. ...

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