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        Research

        Study protocol for controlled human infection for penicillin G against Streptococcus pyogenes: a double-blinded, placebo-controlled, randomised trial to determine the minimum concentration required to prevent experimental pharyngitis (the CHIPS trial)

        Regular intramuscular benzathine penicillin G injections have been the cornerstone of rheumatic heart disease (RHD) secondary prophylaxis since the 1950s. As the pharmacological correlate of protection remains unknown, it is difficult to recommend changes to this established regimen. Determining the minimum effective penicillin exposure required to prevent Streptococcus pyogenes infection will accelerate development of new long-acting penicillins for RHD prevention as well as inform opportunities to improve existing regimens. The CHIPS trial will address this knowledge gap by directly testing protection afforded by different steady state plasma concentrations of penicillin in an established model of experimental human S. pyogenes pharyngitis. ...

        News & Events

        Congratulations to the Embrace 2023 Research Award winners

        Embrace 2023 Research Award winners Zoe Waters and Pulan Bai. ...

        News & Events

        Autism research conference

        The CliniKids research team had a busy few days at the annual International Society for Autism Research (INSAR) conference held in Melbourne recently. ...

        Research

        Burden of drug-resistant tuberculosis among contacts of index cases: A protocol for a systematic review

        People having close contact with drug-resistant tuberculosis (DR-TB) patients are at increased risk of contracting and developing the disease. However, no comprehensive review has been undertaken to estimate the burden of DR-TB among contacts of DR-TB patients. Therefore, the current systematic review will quantify the prevalence and incidence of DR-TB among contacts of DR-TB patients. ...

        News & Events

        Pre-term kids get green light to exercise

        Parents of children born prematurely have expressed concerns about their child’s lung health when they exercise, with symptoms such as breathlessness. ...

        Research

        MACROD2 gene associated with autistic-like traits in a general population sample

        The MACROD2 gene is a strong positional candidate risk factor for autistic-like traits in the general population ...

        PhD student - Clinical Epigenetics

        The Clinical Epigenetics team at Telethon Kids Institute is engaged in understanding the links between the molecular hallmarks of epigenetic control ...

        Research

        Upskilling Service Providers on LGBTQA+ Suicide Prevention

        Penelope Yael Rikki Kirsty Strauss Perry Battersby-Coulter Hird PS YP RBC KH BA, MPH, PhD BPsych (Hons) MPsych (Clin) PhD BA (Psych), MYMH, MPH ( ...

        Research

        Walkern Katatdjin (Rainbow Knowledge)

        Shakara Yael Bep Liddelow-Hunt Perry Uink SLH YP BU BPhil(Hons) BPsych (Hons) MPsych (Clin) PhD BPsych(Hons.), MAppPsy(Clinical), PhD Research ...

        Research

        A scoping review of trans and gender diverse children and adolescents’ experiences of physical activity, sport, and exercise participation

        This study investigated the potential of using SARS-CoV-2 viral Increasing young people's physical activity, along with their motivation and confidence to be active, is widely advocated for supporting desirable health outcomes. Trans and gender diverse (henceforth; trans) young people experience significant physical activity-related barriers compared to cisgender (i.e., an individual for whom gender identity and sex presumed at birth are in alignment) peers. ...

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