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        Research

        Nasal airway epithelial repair after very preterm birth

        Nasal epithelial cells from very preterm infants have a functional defect in their ability to repair beyond the first year of life, and failed repair may be associated with antenatal steroid exposure. ...

        Research

        Variants associated with HHIP expression have sex-differential effects on lung function

        Lung function is highly heritable and differs between the sexes throughout life. However, little is known about sex-differential genetic effects on lung function. We aimed to conduct the first genome-wide genotype-by-sex interaction study on lung function to identify genetic effects that differ between males and females. ...

        Research

        Living with lung disease: experimental models to assess the long-term effects of prematurity

        Laboratory models provide an important tool in helping to understand the cellular and molecular drivers of respiratory disease. Many animal models exist that model the neonatal outcomes of preterm birth. ...

        Research

        Feasibility of unsedated lung MRI in young children with cystic fibrosis

        Kathryn Ramsey KR BSc (Hons), PhD Co-Head, Children's Lung Health kathryn.ramsey@telethonkids.org.au Co-Head, Children's Lung Health Associate ...

        Research

        Longitudinal effects of prenatal exposure to plastic-derived chemicals and their metabolites on asthma and lung function from childhood into adulthood

        Environmental exposure to phthalates and bisphenol A (BPA), chemicals used in the production of plastics, may increase risk for asthma and allergies. However, little is known about the long-term effects of early life exposure to these compounds. ...

        Research

        The cost of respiratory hospitalizations in children with cerebral palsy

        To establish the burden of respiratory illness in cerebral palsy (CP) on the Western Australian health care system by quantifying the costs of respiratory hospitalizations in children with CP, compared with non-respiratory hospitalizations. ...

        Research

        No association between in utero exposure to emissions from a coalmine fire and post-natal lung function

        Studies linking early life exposure to air pollution and subsequent impaired lung health have focused on chronic, low-level exposures in urban settings. We aimed to determine whether in utero exposure to an acute, high-intensity air pollution episode impaired lung function 7-years later. ...

        Research

        Bronchopulmonary dysplasia: Rationale for a pathophysiological rather than treatment based approach to diagnosis

        This review describes the evolution of bronchopulmonary dysplasia definitions, evaluates the benefits and limitations of each approach ...

        Research

        Bronchodilator responsiveness in children with asthma is not influenced by spacer device selection

        Spacer device was not associated with clinically important differences in lung function following bronchodilator inhalation in children with asthma ...

        Research

        Association between diesel engine exhaust exposure and lung function in Australian gold miners

        Diesel engine exhaust exposures were higher in underground miners and had a negative association with their lung function over a single 12-h shift ...

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