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        Research

        Lung function in African infants in the Drakenstein child health study impact of lower respiratory tract illness

        Early life lower respiratory tract illness impairs lung function at 1 year, independent of baseline lung function ...

        Research

        Theory-Based Design and Development of a Socially Connected, Gamified Mobile App for Men About Breastfeeding (Milk Man)

        The development of Milk Man followed a best practice approach, including the involvement of a multidisciplinary team and grounding in behavior change theory ...

        Research

        Lack of replication for the myosin-18B association with mathematical ability in independent cohorts

        Twin studies indicate that dyscalculia (or mathematical disability) is caused partly by a genetic component, which is yet to be understood at the molecular... ...

        Research

        The Dyslexia Candidate Locus on 2p12 Is Associated with General Cognitive Ability and White Matter Structure

        To further explore the effect of disorder-associated genes on cognitive functions, we investigated whether they play a role in broader cognitive traits. ...

        Research

        Guidelines for pregnancy: What's an acceptable risk, and how is the evidence (finally) shaping up?

        This paper reviews the evidence from systematic reviews and meta-analyses examining the risk from low and moderate levels of prenatal alcohol exposure. ...

        Research

        The anti-inflammatory actions of IL-4 in human monocytes are not mediated by IL-10, RP105 or the kinase activity of RIPK2

        The anti-inflammatory actions of IL-4 in activated human monocytes may reflect transcriptional regulation of genes involved in TLR signaling pathways. ...

        Research

        Lung homing T-cell generation is dependent on strength and timing of antigen delivery to lymph nodes

        Inhaled allergens are known for their immediate and ongoing effects in the respiratory tract (RT). ...

        Research

        Gene regulation by 1,25-dihydroxyvitamin D3 in CD4+CD25+ cells is enabled by IL-2

        Vitamin D may be responsible for reducing the development and severity of autoimmune and allergic diseases. Topically applied 1,25-dihydroxyvitamin D(3) (1,25(O ...

        Research

        Evidence for Distinct Cognitive Profiles in Autism Spectrum Disorders and Specific Language Impairment

        This finding supports distinct cognitive profiles in ASD and SLI and may provide further evidence for distinct aetiological mechanisms in the two conditions. ...

        Research

        Population and Public Health Perspectives on Late Language Emergence at 24 Months as a Risk Indicator for Language Impairment at 7 Years

        The emergence of language during the toddler period is one of the most striking accomplishments in young children's development. ...

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