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        Research

        Using acute tryptophan depletion to investigate predictors of treatment response in adolescents with major depressive disorder

        The major hypothesis of this study is that acute tryptophan depletion will be negatively associated with mood and cognitive functioning ...

        Research

        B Part of It protocol: a cluster randomised controlled trial to assess the impact of 4CMenB vaccine on pharyngeal carriage of Neisseria meningitidis in adolescents

        The SA MenB vaccine carriage study aims to assess the impact of 4CMenB on carriage of N. meningitidis in adolescents ...

        Research

        Multiple-breath washout outcomes are sensitive to inflammation and infection in children with cystic fibrosis

        The lung clearance index may be a useful surveillance tool for monitoring the presence and extent of lower airway inflammation and infection ...

        Research

        Maternal alcohol use disorder and subsequent child protection contact: A record-linkage population cohort study

        We examined the relationship between a maternal alcohol-use diagnosis, and the timing of diagnosis, and child protection outcomes in a WA population cohort. ...

        Research

        Early lung disease in infants and preschool children with cystic fibrosis: What have we learned and what should we do about it?

        This review summarizes what we have learned about early lung disease in children with CF and discusses the implications for clinical practice and research ...

        Research

        Adherence to secondary prophylaxis for rheumatic heart disease is underestimated by register data.

        Adequate resources are needed for maintenance of data quality in acute rheumatic fever/ rheumatic heart disease registers to ensure provision of evidence-based care and accurate assessment of program impact. ...

        Research

        Determinants of early-life lung function in African infants

        To assess the determinants of early lung function in African infants. ...

        Research

        Altered regulatory T-cell fractions and Helios expression in clinically isolated syndrome: clues to the development of multiple sclerosis

        These results indicate that T regulatory (Treg) and follicular T regulatory (Tfr) impairment is an early feature in MS. ...

        Research

        Worries, 'weirdos', neighborhoods and knowing people: a qualitative study with children and parents regarding children's independent mobility

        This study involved focus groups with 132 children and 12 parents in primary and secondary school in Victoria to explore children's independent mobility. ...

        Research

        Creating community indicators for early childhood development: challenges and innovations from the kids in communities study

        The community (or neighbourhood) is seen as a potential point of intervention for improving early childhood development outcomes through place-based approaches targeting all children. Yet there are insufficient robust data to guide policy and practice. Developing community factors for early childhood development is one way to facilitate more informed, evidence-based community action. This paper discusses the methodological learnings from the Kids in Communities Study, an Australian investigation into community-level factors important for early childhood development, including some of the challenges and innovations associated with the measurement and development of indicators. ...

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