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        Research

        New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals

        We investigated immune and non-immune related genes to determine other factors required for the development of Abacavir hypersensitivity syndrome ...

        Research

        Narrowband UVB phototherapy reduces TNF production by B-cell subsets stimulated via TLR7 from individuals with early multiple sclerosis

        At the end of a 60-day course of narrowband UVB phototherapy, administered to individuals with early multiple sclerosis, there were changes in the relative proportions of circulating B-cell subsets. This study investigated phototherapy-associated changes to cytokine responses of B cells when exposed to a TLR7 ligand. ...

        Research

        Planning and clinical role of acute medical home care services for COVID-19: consensus position statement by the Hospital-in-the-Home Society Australasia

        During a pandemic when hospitals are stretched and patients need isolation, the role of hospital-in-the-home (HITH) providing acute medical care at home has never been more relevant. We aimed to define and address the challenges to acute home care services posed by the COVID-19 pandemic. ...

        Research

        Tobacco smoking and mental disorders in Australian adolescents

        This study aimed to (1) examine the strength of the association between mental disorders/mental health problems, risk behaviours and tobacco smoking among Australian adolescents, (2) compare rates of tobacco smoking among Australian adolescents with major depressive disorder, attention-deficit/hyperactivity disorder and/or conduct disorder in 2013/14 vs 1998, and (3) identify the extent to which an association between tobacco smoking and mental health problems among adolescents can be attributed to non-mental health risk factors. ...

        Research

        Germline Elongator mutations in Sonic Hedgehog medulloblastoma

        Genetic predisposition to proteome instability may be a determinant in the pathogenesis of paediatric brain cancers ...

        Research

        Differences in stroke risk and cardiovascular mortality for Aboriginal and other Australian patients with atrial fibrillation

        Stroke risk and cardiovascular mortality are markedly higher for Aboriginal than non-Aboriginal patients with atrial fibrillation, particularly for patients under 60 ...

        Research

        Rheumatic heart disease in pregnancy: Profile of women admitted to a Western Australian tertiary obstetric hospital

        This retrospective study assessed maternal and perinatal outcomes for women with rheumatic heart disease admitted to the largest tertiary obstetric hospital ...

        Research

        Higher frequency of vertebrate-infecting viruses in the gut of infants born to mothers with type 1 diabetes

        We demonstrate a distinct gut virome profile in infants of mothers with type 1 diabetes, which may influence health outcomes later in life ...

        Research

        Misgendering and experiences of stigma within health care settings for transgender individuals

        Misgendering within the health care system can significantly affect the mental and physical health of transgender individuals ...

        Research

        A spatio-temporal analysis to identify the drivers of malaria transmission in Bhutan

        Hot spots and clusters of both species were isolated in the central southern part of Bhutan bordering India ...

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