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        Research

        Differential Sensitivity of Human Hepatocellular Carcinoma Xenografts to an IGF-II Neutralizing Antibody May Involve Activated STAT3

        These findings implicate the activation of STAT3 as one pathway that may mediate resistance to IGF-II-targeted therapy in HCC ...

        News & Events

        New research links poor language to lack of Vitamin D in womb

        New research has found that children of mums who had low levels of Vitamin D during pregnancy are twice as likely to have language difficulties. ...

        Research

        Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age

        We identified numerous CpGs differentially methylated in relation to gestational age at birth that appear to reflect fetal developmental processes across tissues ...

        News & Events

        Framing messages for social change

        The nuanced message conveys the foundational importance of child development in the early years but avoids triggering concerns there are no opportunities to intervene at a later age. ...

        Research

        ErbB4 in the brain: Focus on high grade glioma

        The epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases (RTKs) consists of EGFR, ErbB2, ErbB3, and ErbB4. These receptors play key roles in cell proliferation, angiogenesis, cell migration, and in some cases, tumor promotion. ...

        Research

        Gene Expression Analyses of the Spatio-Temporal Relationships of Human Medulloblastoma Subgroups during Early Human Neurogenesis

        Medulloblastoma is the most common form of malignant paediatric brain tumour and is the leading cause of childhood cancer related mortality. ...

        Research

        National Case-Control Study of Childhood Brain Tumours

        Liz Carol Milne Bower E C MPH PhD MBBS MSc PhD FAFPHM DLSHTM FPHA Honorary Emeritus Fellow Senior Principal Research Fellow, Alcohol and Pregnancy & ...

        Research

        The relationship between pitch contours in infant-directed speech and early signs of autism in infancy

        Mother-infant interactions during the first year of life are crucial to healthy infant development. The infant-directed speech (IDS), and specifically pitch contours, used by mothers during interactions are associated with infant language and social development. ...

        Research

        Use of bevacizumab as a single agent or in adjunct with traditional chemotherapy regimens in children with unresectable or progressive low-grade glioma

        Bevacizumab is well tolerated and appears most effective for rapid tumor control to preserve vision and improve morbidity ...

        News & Events

        Telethon Kids Institute Cancer Researcher recognised in 2021 Business Events Perth Aspire Awards

        One of Telethon Kids Institute’s leading young researchers will travel to the world’s premier conference on childhood brain cancer. ...

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