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        Research

        Promoter-level expression clustering identifies time development of transcriptional regulatory cascades initiated by ERBB receptors in breast cancer cells

        The analysis of CAGE (Cap Analysis of Gene Expression) time-courses has been applied to examine the dynamics of enhancer and promoter by sequentially... ...

        Research

        A phase 2 open-label safety and immunogenicity study of a meningococcal B bivalent rLP2086 vaccine in healthy adults

        No currently licensed and available vaccine has been shown to provide broad protection against endemic MnB disease. ...

        Research

        Safety and immunogenicity of a booster dose of a 3-antigen Staphylococcus aureus vaccine (SA3Ag) in healthy adults: A randomized phase 1 study

        Immune responses after the initial vaccination persisted for the 12 months studied, with little additional response after the booster dose at 6 months ...

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        Every Friday: Child Health Research Seminars 2014

        Dr Howlett completed her PhD studies in 2009 at the MCRI in Melbourne, where she worked on gastric cancer cell signaling...a ...

        Research

        Women's knowledge and attitudes regarding alcohol consumption in pregnancy: a national survey

        Alcohol exposure in pregnancy is a common and modifiable risk factor for poor pregnancy and child outcomes. ...

        Research

        Maternal diet modulates the infant microbiome and intestinal Flt3L necessary for dendritic cell development and immunity to respiratory infection

        Poor maternal diet during pregnancy is a risk factor for severe lower respiratory infections in the offspring, but the underlying mechanisms remain elusive. Here, we demonstrate that in mice a maternal low-fiber diet led to enhanced LRI severity in infants because of delayed plasmacytoid dendritic cell recruitment and perturbation of regulatory T cell expansion in the lungs. ...

        Research

        Genome-wide meta-analysis of macronutrient intake of 91,114 European ancestry participants from the cohorts for heart and aging research in genomic epidemiology

        Here, we identifyied 12 suggestively significant loci associated with intake of any macronutrient in 91,114 European ancestry participants ...

        Research

        Response after one dose of monovalent influenza A (H1n1) 2009 vaccine in infants and children - preliminary report

        To assess the immunogenicity and safety of a 2009 influenza A(H1N1) vaccine in children. ...

        Research

        Dietary patterns are associated with cognition among older people with mild cognitive impairment

        This study examined the cross-sectional association between dietary patterns & cognition in a sample of 249 people, 65-90 years, with mild cognitive impairment ...

        Research

        A systematic review of risk factors for cerebral palsy in children born at term in developed countries

        The aim of this study was to conduct a systematic review in order to identify the risk factors for cerebral palsy (CP) in children born at term. ...

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