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        Research

        Lessons learned in genetic research with Indigenous Australian participants

        We reflect on the lessons learned from a recent genome‐wide association study of rheumatic heart disease with Aboriginal Australian participants ...

        Research

        Low-dose UV radiation before running wheel access activates brown adipose tissue

        When combined with physical activity, low-dose UVR may more effectively limit adiposity and modulate metabolic and immune pathways in iBAT ...

        Research

        Examining parent use of specific intervention techniques during a 12-week training program based on the Early Start Denver Model

        This study included five mothers of young children with autism who participated in a 12-week parent training program based on the Early Start Denver Model ...

        Research

        Impact of HIV and antiretroviral drug exposure on lung growth and function over 2 years in an African Birth Cohort

        HIV exposure is associated with altered lung function in early life, with a vulnerable HIV-exposed uninfected subgroup based on maternal disease severity ...

        Research

        Recalling our day in the sun: comparing long-term recall of childhood sun exposure with prospectively collected parent-reported data

        Group data from retrospective recall of sun-related behaviours may be of limited value in studying the relationship between sun exposure and health outcomes; ...

        Research

        Network using Michaelis–Menten kinetics: constructing an algorithm to find target genes from expression data

        We derived a simple ordinary differential equation-based model using Michaelis–Menten Kinetics to process the microarray data ...

        Research

        Pneumococcal conjugate vaccine primes mucosal immune responses to pneumococcal polysaccharide vaccine booster in Papua New Guinean children

        Invasive pneumococcal disease remains a major cause of hospitalization and death in Papua New Guinean (PNG) children. We assessed mucosal IgA and IgG responses in PNG infants vaccinated with pneumococcal conjugate vaccine (PCV) followed by a pneumococcal polysaccharide vaccine (PPV) booster. ...

        Research

        Energy drink intake is associated with insomnia and decreased daytime functioning in young adult females

        To investigate the association between energy drink (ED) use and sleep-related disturbances in a population-based sample of young adults from the Raine Study. ...

        Research

        Transplacental Innate Immune Training via Maternal Microbial Exposure: Role of XBP1-ERN1 Axis in Dendritic Cell Precursor Programming

        We recently reported that offspring of mice treated during pregnancy with the microbial-derived immunomodulator OM-85 manifest striking resistance to allergic airways inflammation, and localized the potential treatment target to fetal conventional dendritic cell (cDC) progenitors. Here, we profile maternal OM-85 treatment-associated transcriptomic signatures in fetal bone marrow, and identify a series of immunometabolic pathways which provide essential metabolites for accelerated myelopoiesis. ...

        Research

        Djaalinj Waakinj (listening talking): Rationale, cultural governance, methods, population characteristics–an urban Aboriginal birth cohort study of otitis media

        The majority of Australian Aboriginal and Torres Strait Islander (hereafter referred to as “Aboriginal”) people live in urban centres. Otitis media (OM) occurs at a younger age, prevalence is higher and hearing loss and other serious complications are more common in Aboriginal than non-Aboriginal children. Despite this, data on the burden of OM and hearing loss in urban Aboriginal children are limited. ...

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