The caregivers in this study have gained valuable knowledge and wisdom through caring for a child with FASD ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• October 2019

Children with medical comorbidities are at greater risk for severe influenza and poorer clinical outcomes. Despite recommendations and funding, influenza vaccine coverage remains inadequate in these children. We aimed to systematically review literature assessing interventions targeting influenza vaccine coverage in children with comorbidities and assess the impact on influenza vaccine coverage. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@ ...

• 1. Telethon Kids Institute
• Projects
• Penicillin Program

Adequate resources are needed for maintenance of data quality in acute rheumatic fever/ rheumatic heart disease registers to ensure provision of evidence-based care and accurate assessment of program impact. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• May 2017

ARF is a classical example of an autoimmune syndrome and is of particular immunological interest because it follows a known antecedent infection with group A... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

Rheumatic fever (RF) prevention, control and surveillance are increasingly important priorities in New Zealand (NZ) and Australia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015

Andrew Chris Gail Susan Peter Whitehouse Watch and listen to Andrew Brennan-Jones Alvares Prescott Jacoby AJ C GA SL PJ PhD PhD PhD MBBS BMedSci PhD ...

• 1. Telethon Kids Institute
• Projects

DYRK1A is a serine/threonine kinase encoded on human chromosome 21 (HSA21) that has been implicated in several pathologies of Down syndrome (DS), including cognitive deficits and Alzheimer's disease. Although children with DS are predisposed to developing leukemia, especially B cell acute lymphoblastic leukemia (B-ALL), the HSA21 genes that contribute to malignancies remain largely undefined. Here, we report that DYRK1A is overexpressed and required for B-ALL. Genetic and pharmacologic inhibition of DYRK1A decreased leukemic cell expansion and suppressed B-ALL development in vitro and in vivo. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Natasha Pete Asha Kevin Pearce Gething Bowen Runions NP PG AC KC PhD (Public Health), PostGrad Dip (Health Promotion), BApp Sc BA MBBS DCH FRACP PhD ...

• 1. Telethon Kids Institute
• Projects

Children in Papua New Guinea (PNG) are at high risk of pneumococcal infections. We investigated pneumococcal carriage rates, serotype distribution, and antimicrobial susceptibility in PNG children after vaccination with 10-valent or 13-valent pneumococcal conjugate vaccines (PCV10; PCV13). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023