Pathogenic fungi can lose virulence after protracted periods of culture, but little is known of the underlying mechanisms. Here, we present the first analysis of DNA methylation flux at a single-base resolution for the plant pathogen B. cinerea and identify differentially methylated genes/genomic regions associated with virulence erosion during in vitro culture. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

This paper documents that children in rural Indonesia participate in a great variety of early childhood education pathways ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• September 2019

The objective of this study is to identify distinct age-related trajectory classes of body mass index (BMI) z-scores from childhood to adolescence ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

To investigate the relationship between time spent outdoors, at particular ages in childhood and adolescence, and myopia status in young adulthood using serum 25-hydroxyvitamin D [25(OH)D] concentration as a biomarker of time spent outdoors. Participants of the Raine Study Generation 2 cohort had 25(OH)D concentrations measured at the 6-, 14-, 17- and 20-year follow-ups. Participants underwent cycloplegic autorefraction at age 20 years, and myopia was defined as a mean spherical equivalent -0.50 dioptres or more myopic. Logistic regression was used to analyse the association between risk of myopia at age 20 years and age-specific 25(OH)D concentrations. Linear mixed-effects models were used to analyse trajectory of 25(OH)D concentrations from 6 to 20 years. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Executive Officer ...

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Doctors are worried by a record number of WA children diagnosed with type 1 diabetes this year, with about 30 per cent more cases than average. ...

• Rio Tinto Children's Diabetes Centre
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This chapter assesses what global evidence tells us about the importance of early childhood education and development... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• January 2013

Rett syndrome is a rare but serious neurological disorder that affects about 1 in 9,000 girls. Even more rarely, boys may be affected. ...

• Rett syndrome and Related Disorders

We have been advised by Novo Nordisk, the manufacturer of NovoRapid, that some circulating Novorapid cartridges may have small circular ...

• Rio Tinto Children's Diabetes Centre
• News and events

There is a need for effective and youth-friendly approaches to suicide prevention, and social media presents a unique opportunity to reach young people. Although there is some evidence to support the delivery of population-wide suicide prevention campaigns, little is known about their capacity to change behaviour, particularly among young people and in the context of social media. Even less is known about the safety and feasibility of using social media for the purpose of suicide prevention. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021