Pat Deborah Holt Strickland PG DH PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic ...

• 1. Telethon Kids Institute
• Our research
• Past teams
• Human Immunology

Pat Deborah Holt Strickland PG DH PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic ...

• 1. Telethon Kids Institute
• Our research
• Early Environment
• Immunobiology & Immunotherapeutic Program
• Pregnancy and Early Life Immunology

Long-standing health inequalities in Australian society that were exposed by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic were described as "fault lines" in a recent call to action by a consortium of philanthropic organizations. With asthma a major contributor to childhood disease burden, studies of its spatial epidemiology can provide valuable insights into the emergence of health inequalities early in life. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• February 2024

Asthma and chronic obstructive pulmonary disease (COPD) are common chronic respiratory diseases, and some patients have overlapping disease features, termed asthma-COPD overlap. Patients characterized with ACO have increased disease severity; however, the mechanisms driving this have not been widely studied. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

High risk for virus-induced asthma exacerbations in children is associated with an IRF7lo immunophenotype, but the underlying mechanisms are unclear. Here, we applied a Systems Biology approach to an animal model comprising rat strains manifesting high versus low susceptibility to experimental asthma, induced by virus/allergen coexposure, to elucidate the mechanism(s)-of-action of the high-risk asthma immunophenotype. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

Environmental exposure to phthalates and bisphenol A (BPA), chemicals used in the production of plastics, may increase risk for asthma and allergies. However, little is known about the long-term effects of early life exposure to these compounds. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

Spacer device was not associated with clinically important differences in lung function following bronchodilator inhalation in children with asthma ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019

Novel loci differentially methylated in newborns represent potential biomarkers of risk of asthma by school age ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

Asthma exacerbations in children can be divided into IRF7hi versus IRF7lo phenotypes with associated differences in clinical phenotypes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

There is evidence to suggest an association between prenatal maternal stress and the development of asthma or other atopic diseases in offspring. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• July 2014