Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary prophylaxis to prevent acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Uncertainties regarding inter-ethnic and preparation variability, and target exposure profiles of BPG injection are key knowledge gaps for RHD control. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Broad community acceptance of a COVID-19 vaccination will be critical for effectively halting the spread of the virus. In this study, we focus on factors that differentiate those who are undecided from those who are either willing or unwilling to accept a prospective COVID-19 vaccine. An online survey in May 2020 assessed Australian adults' willingness to receive a COVID-19 vaccine (yes, maybe, no). A multinomial logistical regression of responses (N = 1,313) was used to identify correlates of vaccine willingness between the three groups. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

To investigate the relationship between time spent outdoors, at particular ages in childhood and adolescence, and myopia status in young adulthood using serum 25-hydroxyvitamin D [25(OH)D] concentration as a biomarker of time spent outdoors. Participants of the Raine Study Generation 2 cohort had 25(OH)D concentrations measured at the 6-, 14-, 17- and 20-year follow-ups. Participants underwent cycloplegic autorefraction at age 20 years, and myopia was defined as a mean spherical equivalent -0.50 dioptres or more myopic. Logistic regression was used to analyse the association between risk of myopia at age 20 years and age-specific 25(OH)D concentrations. Linear mixed-effects models were used to analyse trajectory of 25(OH)D concentrations from 6 to 20 years. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

There is a global trend towards place-based initiatives (PBIs) to break the cycle of disadvantage and promote positive child development. Co-location is a common element of these initiatives and is intended to deliver more coordinated services for families of young children. This paper examines how co-locating early childhood services (ECS) from health and education in Child and Family Centres (CFCs) has impacted collaboration between services. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

A review of cases informed a change from a "3 + 0" infant schedule to a "2 + 1" schedule ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

Here, the role, status, and directions in Group A Streptococcus vaccines research are discussed ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

To prevent persistent victimization, schools and teachers need to be better equipped to respond effectively when a student first becomes a target of bullying ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

The acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

We identified the existence of more than 290 clinically associated genomic phylogroups across 22 countries, highlighting challenges in designing vaccines of global utility ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

This review discusses the available evidence base to help provide practical guidance when considering probiotics in practice ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019