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        Research

        Initial Validation and Reliability of the CDKL5 Deficiency Disorder Hand Function Scale (CDD-Hand)

        Pathogenic variants in the CDKL5 gene result in CDKL5 deficiency disorder (CDD), which is characterized by early-onset epilepsy, severe developmental delay, and often, cortical visual impairment. Validated clinical outcome measures are needed for future clinical trials to be successful. This study aimed to adapt the Rett Syndrome Hand Function Scale for CDKL5 deficiency disorder and evaluate its feasibility, acceptability, content validity, and reliability. ...

        Research

        Negative impact of insomnia and daytime sleepiness on quality of life in individuals with the cyclin-dependent kinase-like 5 deficiency disorder

        Cyclin-dependent kinase-like 5 (CDKL5) gene pathogenic variants result in CDKL5 deficiency disorder (CDD). Early onset intractable epilepsy and severe developmental delays are prominent symptoms of CDD. Comorbid sleep disturbances are a major concerning symptom for families. ...

        Research

        Safety and immunogenicity of pneumococcal conjugate vaccines in a high-risk population: a randomised controlled trial of PCV in Papua New Guinean infants

        Infant vaccination with 3 doses of PCV10 or PCV13 is safe and immunogenic in a highly endemic setting ...

        Research

        Validating the rett syndrome gross motor scale

        The Rett Syndrome Gross Motor Scale could be an appropriate measure of gross motor skills in clinical practice and clinical trials ...

        Research

        Antecedents of hospital admission for deliberate self-harm from a 14-year follow-up study using data-linkage

        A prior episode of deliberate self-harm (DSH) is one of the strongest predictors of future completed suicide. Identifying antecedents of DSH may inform strategi ...

        Research

        Antecedents of teenage pregnancy from a 14-year follow-up study using data linkage

        This study identified possible antecedents of teenage pregnancy using linked data from administrative sources to create a 14-year follow-up from a cross-sect... ...

        Research

        Evidence of a complex association between dose, pattern and timing of prenatal alcohol exposure and child behaviour problems

        There is a lack of evidence regarding the effect of dose, pattern and timing of prenatal alcohol exposure and behaviour problems in children aged 2 years. ...

        Research

        Djaalinj Waakinj Ear Portal: An ENT and Audiology referral pathway for improving access to ear and hearing services for Aboriginal children in the metropolitan area using telehealth

        Chris Peter Deborah Valerie Karina Natasha Tamara Greta Kerryn Brennan-Jones Richmond Lehmann Swift Tao Morrison Veselinovic Bernabei Gidgup C PC D ...

        Research

        Developmental Pathways in WA Children Project (Developmental Pathways Project)

        Rebecca Fiona Melissa Helen Steve Desiree Glauert Stanley O'Donnell Leonard Zubrick Silva RA FJ M HM SR DS BPsych (Hons) PhD FAA FASSA MSc MD FFPHM ...

        Research

        Healthy Ears Clinical Trial: A telehealth-facilitated randomised-controlled trial utilising a health promotion intervention to resolve otitis media with effusion for children won specialist Ear, Nose and Throat (ENT) waiting lists

        Chris Peter Valerie Lea-Ann Ruth Jaimee Melinda Charlie Elke Tamara Robyn Brennan-Jones Richmond Swift Kirkham Thornton Rich Edmunds McLeod Seppanen ...

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