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        Research

        Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection

        Benzathine penicillin G has been used as monthly deep intramuscular (IM) injections since the 1950s for secondary prevention of acute rheumatic fever and rheumatic heart disease (RHD). Injection frequency and pain are major programmatic barriers for adherence, prompting calls for development of better long-acting penicillin preparations to prevent RHD. ...

        Research

        Strengthening health systems to support children with neurodevelopmental disabilities in Fiji—A commentary

        Leadership and collaboration has resulted in increased capacity in the Fijian health system to support children with neurodevelopmental disabilities ...

        Research

        Inter-rater and intra-rater reliability and agreement of echocardiographic diagnosis of rheumatic heart disease using the World Heart Federation evidence-based criteria

        The WHF echocardiographic criteria enable reproducible categorisation of echocardiograms as definite RHD versus no or borderline RHD ...

        Research

        Indigenous compared with non-Indigenous Australian patients at entry to specialist palliative care: Cross-sectional findings from a multi-jurisdictional dataset

        Indigenous patients are substantially underrepresented in care by services participating in the nationwide specialist palliative care ...

        Research

        Evaluation of a phased pneumococcal conjugate vaccine introduction in Mongolia using enhanced pneumonia surveillance and community carriage surveys

        The enhanced surveillance system in Mongolia will facilitate assessment of PCV13 impact on pneumonia, with radiological confirmed disease as the primary outcome ...

        Research

        Rheumatic Heart Disease Worldwide: JACC Scientific Expert Panel

        The authors present a variety of pressing clinical research questions on optimal RHD prevention and advanced care ...

        Research

        The microbiology of impetigo in Indigenous children

        Prevalence and antimicrobial resistance of impetigo pathogens in a randomised, controlled trial of impetigo treatment conducted in remote Indigenous communities ...

        Research

        Development of an opsonophagocytic killing assay for Group A Streptococcus

        Group A Streptococcus (GAS) or Streptococcus pyogenes is responsible for an estimated 500,000 deaths worldwide each year. ...

        Research

        Missing voices: Profile and extent of acquired communication disorders in Aboriginal and non-Aboriginal adult stroke survivors in Western Australia

        The needs of Aboriginal stroke patients with acquired communication disorder should inform appropriate service design for speech pathology and rehabilitation ...

        Research

        Pediatric sepsis in the developing world.

        Sepsis is the leading killer of children worldwide, but this is not reflected in estimates of global mortality. ...

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