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        Research

        Safety and immunogenicity of a meningococcal B bivalent rLP2086 vaccine in healthy toddlers Aged 18-36 months

        A bivalent, recombinant, factor H-binding protein (rLP2086) vaccine was developed to protect against invasive Neisseria meningitidis serogroup B (MnB) in... ...

        Research

        A bivalent Neisseria meningitidis recombinant lipidated factor H binding protein vaccine in young adults:

        Neisseria meningitidis is a leading cause of meningitis and septicaemia, but a broadly-protective vaccine against endemic serogroup B disease is not licensed... ...

        Research

        Can linked emergency department data help assess the out-of-hospital burden of acute lower respiratory infections

        There is a lack of data on the out-of-hospital burden of acute lower respiratory infections (ALRI) in developed countries. ...

        Research

        Idiosyncratic nature of voriconazole photosensitivity in children undergoing cancer therapy

        In adults, the unpredictability of voriconazole pharmacokinetics, particularly in those patients receiving chemotherapy, is well recognised. A paucity of... ...

        Research

        Impacts on influenza A(H1N1)pdm09 infection from cross-protection of seasonal trivalent influenza vaccines and A(H1N1)pdm09 vaccines: Systematic review and meta-analyses

        We did a systematic literature search to identify observational and/or interventional studies reporting cross-protection of TIV and A(H1N1)pdm09... ...

        Research

        Cross-protective efficacy of HPV-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by non-vaccine oncogenic HPV types

        We evaluated the efficacy of the human papillomavirus HPV-16/18 AS04-adjuvanted vaccine against non-vaccine oncogenic HPV types. ...

        Research

        Histiologic chorioamnionitis is associated with reduced incidence of late-onset sepsis in very preterm infants

        Histologic chorioamnionitis (HCA) is implicated in the onset of preterm labor and delivery. Chorioamnionitis is a known risk factor for early-onset sepsis... ...

        Research

        High detection rates of nucleic acids of a wide range of respiratory viruses in the nasopharynx and the middle ear

        Both bacteria and viruses play a role in the development of acute otitis media, however, the importance of specific viruses is unclear. ...

        Research

        Immunogenicity and safety of a combined Haemophilus influenzae type b-Neisseria

        Neisseria meningitidis serogroups B, C, and Y cause most meningococcal disease in industrialized countries... ...

        Research

        Safety and Immunogencity of a Prototype Adjuvanted Inactivated Split-Virus Influenza A (H5N1) Vaccine in Infants and Children

        Highly pathogenic avian influenza A virus (H5N1) is a leading candidate for the next influenza pandemic, and infants and children may play an important role... ...

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