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        The power of pooches: pre-schoolers benefit from having a family dog

        The benefits of owning a dog start even earlier than previously thought show new research from Telethon Kids Institute. ...

        Research

        Inflammatory bowel diseases: interrelationships between dietary vitamin D, exposure to UV radiation and the fecal microbiome

        This review explores the interaction of vitamin D, and ultraviolet radiation, with the intestinal innate and adaptive immune systems ...

        Research

        Developmental vitamin D deficiency increases foetal exposure to testosterone

        Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders which are more common in males. The 'prenatal sex steroid' hypothesis links excessive sex-steroid exposure during foetal life with the behavioural differences observed in ASD. However, the reason why sex steroid exposure may be excessive remains unclear. Epidemiological studies have identified several environmental risk factors associated with ASD, including developmental vitamin D (DVD) deficiency. ...

        Research

        Clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation (CASSETTE)-an open-labelled pilot randomized controlled trial

        Combination antibiotic therapy with an antitoxin agent, such as clindamycin, is included in some guidelines for severe, toxin-mediated Staphylococcus aureus infections. The evidence to support this practice is currently limited to in vitro, animal and observational human case-series data, with no previous randomized controlled trials (RCTs). ...

        Research

        Mucormycosis in Children: Review and Recommendations for Management

        we summarize the literature on the epidemiology and diagnosis of this invasive fungal infection and provide suggestions on the management of mucormycosis in children ...

        News & Events

        More research needed into mums smoking and childhood brain tumours

        Researchers from Perth's Telethon Institute are calling for further investigation into a potential link between maternal smoking and childhood brain tumours. ...

        Research

        Developments in the field of allergy in 2014 through the eyes of Clinical and Experimental Allergy

        The pathogenesis of asthma continues to be a major topic of interest to our authors with reviews and original papers on the role of viruses, mechanisms of... ...

        Research

        Early life rhinovirus infection exacerbates house-dust-mite induced lung disease more severely in female mice

        Early life rhinovirus infection influences the development of house-dust-mite induced lung disease in female, but not male mice ...

        Research

        Overcoming Challenges to Make Bacteriophage Therapy Standard Clinical Treatment Practice for Cystic Fibrosis

        Individuals with cystic fibrosis (CF) are given antimicrobials as prophylaxis against bacterial lung infection, which contributes to the growing emergence of multidrug resistant (MDR) pathogens isolated. Pathogens such as Pseudomonas aeruginosa that are commonly isolated from individuals with CF are armed with an arsenal of protective and virulence mechanisms, complicating eradication and treatment strategies. ...

        Research

        Exposure to Solar UVR Suppresses Cell-Mediated Immunization Responses in Humans: The Australian Ultraviolet Radiation and Immunity Study

        Higher UVR exposure at antigen sensitization was associated with a reduced delayed-type hypersensitivity response and altered T helper type 17 kinetics ...

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