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        About ORIGINS

        The ultimate goal of The ORIGINS Project is to reduce the rising epidemic of non-communicable diseases through 'a healthy start to life'. ...

        Research

        Sex-Specific Environmental Impacts on Initiation and Progression of Multiple Sclerosis

        The immunological mechanisms that contribute to multiple sclerosis (MS) differ between males and females. Females are 2-3 times more likely to develop MS compared to males, however the reason for this discrepancy is unknown. Once MS is established, there is a more inflammatory yet milder form of disease in females whereas males generally suffer from more severe disease and faster progression, neural degradation, and disability. ...

        Research

        Perspectives on the essential skills of healthcare decision making in children and adolescents with intellectual disability

        Involvement in healthcare decisions is associated with better health outcomes for patients. For children and adolescents with intellectual disability, parents and healthcare professionals need to balance listening to a child's wishes with the responsibility of keeping them safe.  ...

        Research

        Perspectives of LGBTQA+ young people on suicide prevention services in Australia

        LGBTQA + people are less likely to access mental health care despite an increased risk of adverse mental health outcomes including suicidal thoughts and behaviours. The present study aimed to explore Australian LGBTQA + young people's perceptions of key factors associated with access to suicide prevention services. ...

        Research

        qPCR assay optimisation for a clinical study comparing oral health risk in Rett syndrome

        This study aimed to validate qPCR assays for specific microbiota, for use on dental plaque samples stored on Whatman FTA cards to compare relative oral health risk in Rett syndrome. ...

        Research

        Can skin exposure to sunlight prevent liver inflammation?

        Here we discuss how skin exposure to sunlight may suppress liver inflammation and the severity of NAFLD. ...

        Research

        Anaemia of Pregnancy, Perinatal Outcomes and Children's Developmental Vulnerability: a Whole-of-Population Study

        The aim of this study is to examine whether anaemia of pregnancy is associated with adverse perinatal outcomes and with children's developmental vulnerability. ...

        Research

        Prolonged school non-attendance in adolescence: a practical approach

        Prolonged school non-attendance in adolescence is complex and represents a critical public health problem due to the range of associated adverse poor outcomes ...

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        Best practice in diabetes care

        Last month, our Centre's co-Director Liz Davis, attended the National Association of Diabetes Centre's (NADC) Symposium in Sydney. ...

        Research

        Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells

        Mature B cells, CR2/CD21 transcription proceeds from a focused TSS regulated by a non-consensus TATA box, an initiator element and downstream promoter element ...

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