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        Research

        Experience of patients with lung cancer and with targeted therapy-related skin adverse drug reactions: A qualitative study

        To explore the experience of non-small-cell lung cancer patients with targeted therapy-related skin adverse drug reactions. ...

        Research

        Cancer Survival and Excess Mortality Estimates among Adolescents and Young Adults in Western Australia, 1982-2004: A Population-Based Study

        A cancer diagnosis in adolescents and young adults conferred substantial survival decrement. ...

        Research

        A surgically optimized intraoperative poly(I:C)-releasing hydrogel prevents cancer recurrence

        Recurrences frequently occur following surgical removal of primary tumors. In many cancers, adjuvant therapies have limited efficacy. Surgery provides access to the tumor microenvironment, creating an opportunity for local therapy, in particular immunotherapy, which can induce local and systemic anti-cancer effects. ...

        Research

        Multi-omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer

        Prostate cancer is the most commonly diagnosed malignancy and the third leading cause of cancer deaths. GWAS have identified variants associated with prostate cancer susceptibility; however, mechanistic and functional validation of these mutations is lacking. ...

        Research

        Lessons learnt from influenza vaccination in immunocompromised children undergoing treatment for cancer

        Influenza infection contributes substantially to global morbidity and mortality, with children undergoing treatment for cancer among the most vulnerable due to immunosuppression associated with disease and treatment. However, influenza remains one of the most common vaccine-preventable diseases. ...

        Unlocking the mysteries of the immune system to tackle childhood cancer

        Dr Joost Lesterhuis and his colleagues in the Sarcoma Translational Research Team are working on an immunotherapy gel that could be applied directly ...

        Research

        Intake of polyphenols from cereal foods and colorectal cancer risk in the Melbourne Collaborative Cohort Study

        Cereal-derived polyphenols have demonstrated protective mechanisms in colorectal cancer (CRC) models; however, confirmation in human studies is lacking. Therefore, this study examined the association between cereal polyphenol intakes and CRC risk in the Melbourne Collaborative Cohort Study (MCCS), a prospective cohort study in Melbourne, Australia that recruited participants between 1990 and 1994 to investigate diet-disease relationships. ...

        News & Events

        Associate Professor Nick Gottardo awarded Cure Brain Cancer Foundation Innovation Grant 2017

        Telethon Kids cancer researcher & clinician Dr Nick Gottardo has been announced as the recipient of an Innovation Grant from the Cure Brain Cancer Foundation. ...

        Research

        Cancer incidence and mortality trends in Australian adolescents and young adults, 1982-2007

        The objective of this study was to describe overall and type-specific cancer incidence and mortality trends among AYAs in Western Australia from 1982-2007... ...

        Research

        Finding new, safer and targeted therapies for paediatric brain cancer that amplify responses to radiation therapy

        Raelene Nick Jessica Annabel Meegan Jacqueline Endersby Golding Buck Short Howlett Whitehouse R NG JB AS MH JW BSc (Hons) PhD BSc DPhil DPhil BMedRes ...

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