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        131-140 of 344 results for 'endgame '

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        Research

        Changes in the clinical and epidemiological features of group A streptococcal bacteraemia in Australia's northern territory

        We aimed to measure the incidence and severity of invasive Group A Strep disease in the NT since 1996. ...

        Research

        Utility of auscultatory screening for detecting rheumatic heart disease in high-risk children in Australia's Northern Territory

        Sensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator. ...

        Research

        Rheumatic heart disease across the Western Pacific: not just a Pacific Island problem

        We aimed to review RHD burden in Western Pacific Region outside Oceania to identify countries with high RHD burden ...

        Research

        Defining target penicillin concentrations for subsequent studies of a reformulated long-acting benzathine penicillin prototype

        Jonathan Tim Carapetis AM Barnett JR TB AM MBBS FRACP FAFPHM PhD FAHMS PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Head of ...

        Research

        Skin Infections

        Skin infections such as impetigo and scabies are highly contagious, and can lead to serious health complications without treatment. These types of skin infections are major problems in remote Aboriginal communities. ...

        Research

        High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin G injections in Ethiopian children and adults with rheumatic heart disease

        Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary prophylaxis to prevent acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Uncertainties regarding inter-ethnic and preparation variability, and target exposure profiles of BPG injection are key knowledge gaps for RHD control. ...

        News & Events

        $11M funding boost for child health

        Researchers at the Telethon Kids Institute have today been awarded more than $11 million in funding from the National Health and Medical Research Council. ...

        Research

        Acceptability of sonicated versus unsonicated reconstituted (powdered) benzathine penicillin G for rheumatic fever prophylaxis

        Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@ ...

        Research

        Rheumatic Heart Disease in Pregnancy: New Strategies for an Old Disease?

        RHD in pregnancy (RHD-P) is associated with an increased burden of maternal and perinatal morbidity and mortality. A sequellae of rheumatic fever resulting in heart valve damage if untreated, RHD is twice as common in women. In providing an historical overview, this commentary provides context for prevention and treatment in the 21 st century. Four underlying themes inform much of the literature on RHD-P: its association with inequities; often-complex care requirements; demands for integrated care models, and a life-course approach. ...

        Research

        Caring for Pregnant Women with Rheumatic Heart Disease: A Qualitative Study of Health Service Provider Perspectives

        Rheumatic heart disease (RHD) persists in low-middle-income countries and in high-income countries where there are health inequities. RHD in pregnancy (RHD-P) is associated with poorer maternal and perinatal outcomes. Our study examines models of care for women with RHD-P from the perspectives of health care providers. ...

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