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        Research

        Regulatory role of IL10 genetic variations in determining allergen-induced TH2 cytokine responses in children

        Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response. ...

        Research

        Do early-life viral infections cause asthma?

        Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known ...

        Research

        UV exposure and protection against allergic airways disease

        Asthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity. ...

        Research

        Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study

        Atopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children. ...

        Research

        Providing feedback on adherence increases use of preventive medication by asthmatic children

        This study investigates the impact of measuring adherence and providing feedback on medication usage by children with unstable asthma. ...

        Research

        Toll-like receptor 2 ligands inhibit Th2 responses to mite allergen

        There is intense interest in the interaction between microbial compounds and allergy. ...

        Research

        Studies on the immunological mechanisms underlying progression versus resolution of asthma between adolescence and adulthood

        Pat Deborah Holt Strickland PG DH PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic ...

        News & Events

        Very preterm babies at risk of declining lung function throughout childhood

        A Telethon Kids Institute study published in The Lancet Child & Adolescent Health has found that survivors of very preterm birth face declining lung function ...

        News & Events

        Telethon Kids Institute researchers share in TPCHRF funding

        Eight Telethon Kids Institute researchers are among those who have received grant funding from the Telethon-Perth Children’s Hospital Research Fund (TPCHRF). ...

        News & Events

        Switch on the immune system early

        Findings by Professor Pat Holt revealed researchers had been heading down the wrong path in their battle strategy against respiratory allergy and asthma. ...

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