Rheumatic heart disease in pregnancy persists in First Nations people in Australia and New Zealand and is associated with major cardiac and perinatal morbidity ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

There is low coverage of the multivalent M protein vaccine in our setting, emphasizing the need to reformulate the vaccine to improve coverage ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• October 2019

The results suggest that timely injection and patient education are priorities for managing ARF and RHD, particularly focusing on child-to-adult transition care ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• January 2020

Contemporary data for the global burden of sore throat and group A Streptococcus (Strep A) pharyngitis are required to understand the frequency of disease and develop value propositions for Strep A vaccines. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

In 2019, the Murdoch Children's Research Institute in partnership with the Fiji Ministry of Health and Medical Services carried out an integrated mass drug administration (MDA) for the treatment of scabies and lymphatic filariasis in the Northern Division of Fiji. We conducted a retrospective micro-costing exercise focused on the cost of scabies control in order to inform budgeting and policy decision making in an endemic setting. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

Vaccine development and implementation decisions need to be guided by accurate and robust burden of disease data. We developed an innovative systematic framework outlining the properties of such data that are needed to advance vaccine development and evaluation, and prioritize research and surveillance activities. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

This report provides an update on the contemporary global and regional policy landscapes relevant to rheumatic heart disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

We estimated the global disease prevalence of and mortality due to rheumatic heart disease over a 25-year period ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• August 2017

The current prophylactic treatment to prevent rheumatic heart disease requires four-weekly intramuscular injection of a suspension of the poorly soluble benzathine salt form of penicillin G (BPG) often for more than 10 years. In seeking to reduce the frequency of administration to improve adherence, biodegradable polymer matrices have been investigated. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

Prevalence of skin sores and scabies in remote Australian Aboriginal communities remains unacceptably high, with Group A Streptococcus (GAS) the dominant pathogen. We aim to better understand the drivers of GAS transmission using mathematical models. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018