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        Research

        Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity

        To gain further insight into the genetic architecture of psoriasis, we conducted a meta-analysis of 3 genome-wide association studies (GWAS) and 2... ...

        Research

        Associations between maternal antioxidant intakes in pregnancy and infant allergic outcomes

        Antioxidant intakes in pregnancy may influence fetal immune programming and the risk of allergic disease. ...

        Research

        Autism spectrum disorder in children born preterm: Role of exposure to perinatal inflammation

        This review aims to summarise and evaluate the potential mechanisms and evidence for the role of prenatal infection on the central nervous system, and how it... ...

        Research

        Analysis of baseline hypothalamic-pituitary-adrenal activity in late adolescence reveals gender specific sensitivity of the stress axis

        We aimed to investigate basal HPA-activity in a normal population in late adolescence, the time of life believed to overlap with HPA-axis maturation... ...

        Research

        Diverging Trends in Gastroenteritis Hospitalizations during Two Decades in Western Australian Aboriginal and Non-Aboriginal Children

        Our findings highlight the need to consider age, ethnicity, seasonality and climate when evaluating rotavirus vaccine programs. ...

        Research

        Setting the RECORD straight: Developing a guideline for the reporting of studies conducted using observational routinely collected data

        There has been a dramatic increase in the availability of "routine data" for research purposes, including data from electronic medical records,... ...

        Research

        Elevated IL-5 and IL-13 responses to egg proteins predate the introduction of egg in solid foods in infants with eczema

        Elevated egg-specific Th2 cytokine responses were established prior to egg ingestion at 4months and were not significantly altered by introduction of egg ...

        Research

        The genetic associations of acute anterior uveitis and their overlap with the genetics of ankylosing spondylitis

        These findings also suggest that variants in ERAP1 have a differential impact on the risk of AAU when compared with AS, and hence the genetic risk for AAU... ...

        Research

        World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics

        Develop evidence-based recommendations about the use of prebiotics in the prevention of allergy ...

        Research

        Early Nutrition as a Major Determinant of 'Immune Health': Implications for Allergy, Obesity and Other Noncommunicable Diseases

        A better understanding of nutritional programming of immune health may lead to dietary strategies that reduce the burden of many inflammatory diseases ...

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