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        Research

        Controlling acute rheumatic fever and rheumatic heart disease in developing countries: Are we getting closer?

        Improved opportunities for the primary prevention of ARF now exist, because of point-of-care antigen tests for Streptococcus pyogenes, and clinical decision... ...

        Research

        A systematic and functional classification of Streptococcus pyogenes that serves as a new tool for molecular typing and vaccine development.

        This publication is a systematic analysis of all Group A Streptococcus M protein variants, to assist in the development of a vaccine. ...

        Research

        Invasive group A streptococcal infection in the Northern Territory, Australia: Case report and review of the literature

        This review article presents the case of infant Aboriginal twins with invasive group A streptococcal infection complicated by streptococcal toxic shock... ...

        Research

        Prevalence of rheumatic heart disease in young adults from New Caledonia

        The prevalence of echocardiographically diagnosed RHD in adults in New Caledonia is estimated at 5.9 per 1000 ...

        Research

        Acute Rheumatic Fever and Chronic Rheumatic Disease

        This chapter describes the epidemiology, pathogenesis, clinical manifestations, diagnostic criteria, and management principles of acute rheumatic fever. ...

        Research

        Developing a human challenge model of GAS infection

        Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@ ...

        Research

        Penicillin Levels for Rheumatic Heart Disease Study - WA Urban Cohort

        Jonathan Carapetis AM JR AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@ ...

        Research

        Sore Throat Melbourne and Perth Study: The Australian Strep A Vaccine Initiative (ASAVI) Urban Pharyngitis Surveillance Study (STAMPS)

        Jonathan Peter Carapetis AM Richmond JR PC AM MBBS FRACP FAFPHM PhD FAHMS MBBS MRCP(UK) FRACP Executive Director; Head, Strep A Translation; ...

        Research

        The economic and health burdens of diseases caused by group A Streptococcus in New Zealand

        In preparation for the future arrival of a group A Streptococcus (GAS) vaccine, this study estimated the economic and health burdens of GAS diseases in New Zealand. The annual incidence of GAS diseases was based on extrapolation of the average number of primary healthcare episodes managed each year in general practices (2014-2016) and on the average number of hospitalizations occurring each year (2005-2014). Disease incidence was multiplied by the average cost of diagnosing and managing an episode of disease at each level of care to estimate the annual economic burden. ...

        Research

        Adherence to secondary prophylaxis for rheumatic heart disease is underestimated by register data.

        Adequate resources are needed for maintenance of data quality in acute rheumatic fever/ rheumatic heart disease registers to ensure provision of evidence-based care and accurate assessment of program impact. ...

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