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        Research

        Genetics of Otitis Media

        Sarra Jenefer Jamieson Blackwell SE JM BSc (Hons) MSc PhD BSc with First Class Honours, PhD, DSc, FMedSci, FAA Senior Research Fellow Head, Genetics ...

        Research

        Genome-wide Association Meta-analysis of Childhood and Adolescent Internalizing Symptoms

        To investigate the genetic architecture of internalizing symptoms in childhood and adolescence. ...

        Research

        Variants near CCNL1/LEKR1 and in ADCY5 and Fetal Growth Characteristics in Different Trimesters

        A recent genome-wide association study identified variants near CCNL1/LEKR1 (rs900400) and in ADCY5 (rs9883204) to be associated with birth weight. ...

        Research

        The -2518bp promoter polymorphism at CCL2/MCP1 influences susceptibility to mucosal but not localized

        Mucosal leishmaniasis (ML) follows localized cutaneous leishmaniasis (CL) caused by Leishmania braziliensis. ...

        Research

        Epigenetics in infectious diseases

        Viruses, bacteria, and parasites have developed strategies to invade and establish long-term infections in their hosts. ...

        Research

        Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed Screens

        The poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput. ...

        Research

        Heritable and environmental determinants of hospitalisation for common childhood illnesses

        Names of investigators Nick de Klerk, Kim Carter, Michelle de Klerk. Infectious diseases are the leading cause of childhood death and health service ...

        Research

        Lack of replication for the myosin-18B association with mathematical ability in independent cohorts

        Twin studies indicate that dyscalculia (or mathematical disability) is caused partly by a genetic component, which is yet to be understood at the molecular... ...

        Research

        Functional validation of variants of unknown significance using CRISPR gene editing and transcriptomics: A Kleefstra syndrome case study

        There are an estimated > 400 million people living with a rare disease globally, with genetic variants the cause of approximately 80% of cases. Next Generation Sequencing (NGS) rapidly identifies genetic variants however they are often of unknown significance. ...

        Research

        Immunogenetics of Parasitic and Bacterial Disease

        Here we focus on more recent well-powered genome-wide association studies, including malaria, leprosy, tuberculosis, and visceral leishmaniasis ...

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