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        Research

        Birthweight and childhood cancer: Preliminary findings from the international childhood cancer cohort consortium (I4C)

        Background Evidence relating childhood cancer to high birthweight is derived primarily from registry and case-control studies. ...

        Research

        Maternal supplementation with folic acid and other vitamins and risk of leukemia in offspring: a childhood leukemia international consortium study

        Our results suggest that maternal prenatal use of vitamins and folic acid reduces the risk of both ALL and AML ...

        Research

        Germ-line and somatic DICER1 mutations in pineoblastoma

        This study suggests that germ-line DICER1 mutations make a clinically significant contribution to PinB, establishing DICER1 as an important susceptibility... ...

        Research

        A pre-clinical model of resistance to induction therapy in pediatric acute lymphoblastic leukemia

        Relapse and acquired drug resistance in T-cell acute lymphoblastic leukemia (T-ALL) remains a significant clinical problem. ...

        Research

        Connective tissue growth factor is expressed in bone marrow stromal cells and promotes interleukin-7-dependent B lymphopoiesis

        Hematopoiesis occurs in a complex bone marrow microenvironment in which bone marrow stromal cells provide critical support to the process through direct cell... ...

        Research

        Comparative drug screening in NUT midline carcinoma

        The NUT midline carcinoma (NMC) is a rare but fatal cancer for which systematic testing of therapy options has never been performed. ...

        Research

        Hepatic sinusoidal obstruction syndrome during chemotherapy for childhood medulloblastoma: Report of a case and review of the literature

        Rishi Sury Nick Kotecha Gottardo RS NG MB ChB (Hons) MRCPCH FRACP PhD MBChB FRACP PhD Co-Head, Leukaemia Translational Research Co-Head, Brain Tumour ...

        Research

        Idiosyncratic nature of voriconazole photosensitivity in children undergoing cancer therapy

        In adults, the unpredictability of voriconazole pharmacokinetics, particularly in those patients receiving chemotherapy, is well recognised. A paucity of... ...

        News & Events

        Childhood cancers not on the rise in SA and NT, but disparity remains for Indigenous children in the NT

        Despite national and global reports of rising incidences of cancer affecting children and young people, a new analysis has found rates of childhood cancer have remained unchanged over the last 30 years in South Australia and the Northern Territory. ...

        News & Events

        Precision medicine offering new hope for kids with aggressive cancers

        A world-first study involving more than 100 cancer researchers and clinicians across Australia – including from Telethon Kids Institute and Perth Children’s Hospital – has shown that precision medicine can significantly improve outcomes for children with high-risk cancer. ...

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