Inflammation and oxidative stress play a key role in the development of bronchopulmonary dysplasia (BPD), possibly contributing to persistent respiratory morbidity after preterm birth. We aimed to assess if inflammatory markers were elevated in exhaled breath condensate (EBC) of infants born very prematurely (< 32 weeks gestation) at 12-16 corrected months of age, and if increased levels were associated with BPD diagnosis and respiratory morbidity. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

Obstructive sleep apnea (OSA) increases the risk of perioperative adverse events in children. While polysomnography remains the reference standard for OSA diagnosis, oximetry is a valuable screening tool. The traditional practice is the manual analysis of desaturation clusters derived from a tabletop device using the McGill oximetry score. However, automated analysis of wearable oximetry data can be an alternative. This study investigated the accuracy of wrist-worn oximetry with automated analysis as a preoperative OSA screening tool. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

This study aimed to determine whether breathing 100% oxygen altered tidal breathing parameters in healthy young children and young children with CF. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

Mannitol challenge tests are used clinically to diagnose asthma and, in particular, exercise-induced broncoconstriction (EIB) in adults and children above 6... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• November 2013

Young people who are overweight/obese are more likely to display expFL during submaximal exercise compared with children of healthy weight. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

In this review article we systematically summarize the evidence for an impact on lung development of 1) maternal ingestion of arsenic contaminated drinking... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

While the majority of pediatric intubations are uncomplicated, the 'Can't intubate, Can't Oxygenate' scenario (CICO) does occur. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Measurements of maximal voluntary inspiratory (Pi max) and expiratory (Pe max) pressures are used in the management of respiratory muscle disease... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• September 2012

Better understanding of evolution of lung function in infants with cystic fibrosis... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• July 2011

Few clinical respiratory laboratories have assessed the impact of changing reference equations on the interpretation of spirometric outcomes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• July 2011