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        Research

        Developmental-associated dysregulation of innate anti-microbial immunity in early life as a determinant of susceptibility to atopic asthma

        Pat Holt PG PhD, DSc, FRCPath, FRCPI, FAA Emeritus Honorary Researcher Patrick.Holt@telethonkids.org.au Emeritus Honorary Researcher Prof Holt ...

        Research

        Comparison of rhinovirus antibody titers in children with asthma exacerbations and species-specific rhinovirus infection

        Asthma exacerbations are associated with human rhinovirus (HRV) infections, and more severe exacerbations are associated with HRV-C. ...

        Research

        Prevention of Allergy/Asthma - New Strategies

        This review focuses on the scientific rationale for early intervention aimed at asthma prophylaxis and discusses therapeutic approaches ...

        Research

        Transcription factor p63 regulates key genes and wound repair in human airway epithelial Basal cells

        The airway epithelium in asthma displays altered repair and incomplete barrier formation. ...

        Research

        Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthma

        These data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important... ...

        Research

        Developments in the field of allergy in 2014 through the eyes of Clinical and Experimental Allergy

        The pathogenesis of asthma continues to be a major topic of interest to our authors with reviews and original papers on the role of viruses, mechanisms of... ...

        Research

        Novel drug targets for asthma and COPD: Lessons learned from in vitro and in vivo models

        This paper is a review of potential novel therapeutic targets or tools for the treatment of asthma and COPD. ...

        Research

        Differential gene network analysis for the identification of asthma-associated therapeutic targets in allergen-specific T-helper memory responses

        Differential network analysis of allergen-induced CD4 T cell responses can unmask covert disease-associated genes and pin point novel therapeutic targets ...

        Research

        The genetic and epigenetic landscapes of the epithelium in asthma

        Genetic factors in airway epithelial cells that are functionally associated with asthma pathogenesis ...

        Research

        Probiotics for treatment and primary prevention of allergic diseases and asthma: looking back and moving forward

        Review treatment and primary prevention studies, recent meta-analyses, and discuss the current understanding of the role of probiotics in this context ...

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