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        171-180 of 1080 results for '2012'

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        Research

        Efficacy of oral amoxicillin-clavulanate or azithromycin for non-severe respiratory exacerbations in children with bronchiectasis (BEST-1)

        Amoxicillin-clavulanate treatment is beneficial in terms of resolution of non-severe exacerbations of bronchiectasis in children ...

        Research

        Systematic analysis of transcription start sites in avian development

        CAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell populations. ...

        Research

        Integrative CAGE and DNA Methylation Profiling Identify Epigenetically Regulated Genes in NSCLC

        Epigenetically regulated genes have a great theranostic potential, especially in tumors with no apparent driver mutations. ...

        Research

        Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.

        We propose that this system provides a model for the differentiation and adaptation of monocytes entering the intestinal lamina propria. ...

        Research

        Intellectual disability: Population-based estimates of the proportion attributable to maternal alcohol use disorder during pregnancy

        The aim of this study was to examine the association between maternal alcohol use disorder and intellectual disability in children. ...

        Research

        CD4+ T cells drive an inflammatory, TNF-α/IFN-rich tumor microenvironment responsive to chemotherapy

        While chemotherapy remains the first-line treatment for many cancers, it is still unclear what distinguishes responders from non-responders. Here, we characterize the chemotherapy-responsive tumor microenvironment in mice, using RNA sequencing on tumors before and after cyclophosphamide, and compare the gene expression profiles of responders with progressors. ...

        Research

        Pregnancy and birth outcomes of mothers with intellectual disability and their infants: Advocacy needed to improve well-being

        For mothers with intellectual disability, modifiable risk factors for adverse outcomes need addressing ...

        Research

        Mapping mammalian cell-type-specific transcriptional regulatory networks using KD-CAGE and ChIP-seq data in the TC-YIK cell line.

        Examining the overlap between genes perturbed in the KD-CAGE experiments and genes with a ChIP-seq peak within 50 kb of their promoter, we identified direct... ...

        Research

        Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive Development

        New research links poor language to lack of Vitamin D in womb. ...

        Research

        Record linkage study of the pathogen-specific burden of respiratory viruses in children

        Reliance on hospital discharge diagnosis codes alone will likely underestimate the burden of respiratory viruses ...

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