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        Research

        Gain of chromosome 21 in hematological malignancies: lessons from studying leukemia in children with Down syndrome

        Structural and numerical alterations of chromosome 21 are extremely common in hematological malignancies. While the functional impact of chimeric transcripts from fused chromosome 21 genes such as TEL-AML1, AML1-ETO, or FUS-ERG have been extensively studied, the role of gain of chromosome 21 remains largely unknown. ...

        News & Events

        School routes swimming in junk food ads

        Perth children are being exposed to thousands of junk food ads every year on their way to and from school, a study led by the Telethon Kids Institute has found. ...

        Research

        Cultures of HRV-C for investigations of pathogenesis in children

        Anthony Belinda Ingrid Kicic Hales Laing A BJ IL BSc (Hons) PhD BSc (Hons) PhD BSc PhD Rothwell Family Fellow; Head, Airway Epithelial Research ...

        Translational Genomics in Leukaemia

        The Translational Genomics in Leukaemia team is focused on identifying the causes of leukaemia, with the goal of developing new targeted treatments to improve quality of care and long-term survival for all children with leukaemia. ...

        Research

        Rhinoviruses A and C elicit long-lasting antibody responses with limited cross-neutralization

        Rhinoviruses (RVs) can cause severe wheezing illnesses in young children and patients with asthma. Vaccine development has been hampered by the multitude of RV types with little information about cross-neutralization. We previously showed that neutralizing antibody (nAb) responses to RV-C are detected twofold to threefold more often than those to RV-A throughout childhood. Based on those findings, we hypothesized that RV-C infections are more likely to induce either cross-neutralizing or longer-lasting antibody responses compared with RV-A infections. ...

        News & Events

        Major focus for children's diabetes research in WA

        Contact us For general inquiries including collaborations, please contact Senior Program Manager Jess Sheppard: Phone: (08) 6456 4616 Email: ...

        Research

        Understanding the relative contributions of the lung, respiratory muscles and the blood vessels to severity of chronic lung disease in very preterm infants (PIFCO Follow-up)

        Graham Ingrid Shannon Hall Laing Simpson GL IL SS BAppSci PhD CRFS FANZSRS FThorSoc FERS BSc PhD BMedSci (hons), PhD Honorary Research Associate Head ...

        Research

        Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group

        Medulloblastoma is curable in approximately 70 % of patients. Over the past decade, progress in improving survival using conventional therapies has stalled... ...

        STARFISH

        About STARFISH Our principles and ways of working Our research questions Collaborators Rheumatic heart disease (RHD) stems from the abnormal immune ...

        Research

        Effects of zinc and vitamin A supplementation on prognostic markers and treatment outcomes of adults with pulmonary tuberculosis: a systematic review and meta-analysis

        Undernutrition is a major risk factor for tuberculosis (TB), which is estimated to be responsible for 1.9 million TB cases per year globally. The effectiveness of micronutrient supplementation on TB treatment outcomes and its prognostic markers (sputum conversion, serum zinc, retinol and haemoglobin levels) has been poorly understood. ...

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