The most urgent areas appear to be to continue monitoring the emergence of novel otopathogens, and the need to develop prevention and preventative therapies ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020

Implementation of lifelong ART of all HIV-infected women has the potential to improve maternal determinants of protective immunity in the young infant ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Six out of ten ‘nicotine-free’ e-cigarette liquids analysed by Telethon Kids Institute researchers contained nicotine as well as an acutely toxic chemical typically found in pesticides and disinfectants. ...

• Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2019
• January

Vlad Guz giving a TEDxKings Park Youth talk in 2023. Source: TEDxKings Park ...

• Embrace @ Telethon Kids
• News and events
• 2024
• March

Results from recent clinical studies suggest potential efficacy of immune training (IT)-based approaches for protection against severe lower respiratory tract infections in infants, but underlying mechanisms are unclear. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

Immunity is distinct in early life and greater precision is required in our understanding of mechanisms of early life protection to inform development of new pediatric vaccines ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

The expression pattern of FcεRI on DC and basophils differentiates asthmatic from non-asthmatic atopic children ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• September 2019

Dysregulated expression of IFN-dependent pathways after respiratory viral infections is a defining immunophenotypic feature of AVB-susceptible infants ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

In both high- and low-income countries, HIV-negative children born to HIV-positive mothers (HIV exposed, uninfected [HEU]) are more susceptible to severe infection than HIV-unexposed, uninfected (HUU) children, with altered innate immunity hypothesized to be a cause. Both the gut microbiome and systemic innate immunity differ across biogeographically distinct settings, and the two are known to influence each other. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020

Here we describe a method by which serial biopsy can be used to validate response to dacomitinib treatment in vivo using a mouse glioblastoma model ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• April 2017