This study aimed to investigate the effects of different macro-environments on asthma genotype-phenotype associations in 2 geographically separated populations ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• February 2010

Citation: Donovan GM, Wang KCW, Elliot JG, James AL, Noble PB. Quantifying airway remodelling for research or clinical purposes: How should we ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• January 2023

We employed a systems biology approach to delineate upper airway gene network patterns underlying asthma exacerbation phenotypes in children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

With up to one in four Australian children now affected by allergic diseases, the potential for the ORIGINS SYMBA Study to positively impact future lives is immense. ...

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Human rhinovirus (RV)-induced exacerbations of asthma and wheeze are a major cause of emergency room presentations and hospital admissions among children. Previous studies have shown that immune response patterns during these exacerbations are heterogeneous and are characterized by the presence or absence of robust interferon responses. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

An improved understanding of the roles of protein kinases in intracellular signalling and disease progression has driven significant advances in protein... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• March 2011

There is evidence to suggest an association between prenatal maternal stress and the development of asthma or other atopic diseases in offspring. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• July 2014

Ingrid Pat Laing Holt IL PG BSc PhD PhD, DSc, FRCPath, FRCPI, FAA Head, Children's Respiratory Science Emeritus Honorary Researcher 6319 1828 ...

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• Projects

Intrauterine growth restriction (IUGR) is associated with asthma. Murine models of IUGR have altered airway responsiveness in the absence of any inflammatory exposure. Given that a primary feature of asthma is airway inflammation, IUGR-affected individuals may develop more substantial respiratory impairment if subsequently exposed to an allergen. This study used a maternal hypoxia-induced mouse model of IUGR to determine the combined effects of IUGR and allergy on airway responsiveness. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

Niamh Troy NT PhD Candidate Niamh.troy@telethonkids.org.au Niamh completed her BSc (Hon) Biomedical Science at Maynooth University, Ireland in 2010 ...

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