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        Research

        Anoctamins and Calcium Signalling: An Obstacle to EGFR Targeted Therapy in Glioblastoma?

        Glioblastoma is the most common form of high-grade glioma in adults and has a poor survival rate with very limited treatment options. There have been no significant advancements in glioblastoma treatment in over 30 years. Epidermal growth factor receptor is upregulated in most glioblastoma tumours and, therefore, has been a drug target in recent targeted therapy clinical trials. ...

        Research

        Allies or enemies? The effect of regulatory T cells and related T lymphocytes on the profibrotic environment in bleomycin-injured lung mouse models

        Idiopathic pulmonary fibrosis (IPF) is characterized by permanent scarring of lung tissue and declining lung function, and is an incurable disease with increase in prevalence over the past decade. ...

        Research

        Effects of climatic factors on COVID-19 transmission in Ethiopia

        Climatic conditions play a key role in the transmission and pathophysiology of respiratory tract infections, either directly or indirectly. However, their impact on the COVID-19 pandemic propagation is yet to be studied. ...

        Research

        The burden of atopic dermatitis and bacterial skin infections among urban-living Indigenous children and young people in high-income countries: A systematic review

        A high burden of bacterial skin infections is well documented in remote-living Indigenous children and young people in high-income countries. ...

        Research

        Preservice teachers’ accuracy in measuring child engagement using a digitised momentary time sampling measure

        Engagement has been identified as an important predictor of student outcomes; therefore, teachers’ ability to accurately and objectively measure student engagement is essential and can assist teachers to make instructional decisions based on data rather than perception. ...

        Research

        Body distribution of impetigo and association with host and pathogen factors

        Impetigo or skin sores are estimated to affect >162 million people worldwide. Detailed descriptions of the anatomical location of skin sores are lacking. ...

        Research

        Neonatal Docosahexaenoic Acid in Preterm Infants and Intelligence at 5 Years

        Docosahexaenoic acid (DHA) is a component of neural tissue. Because its accretion into the brain is greatest during the final trimester of pregnancy, infants born before 29 weeks' gestation do not receive the normal supply of DHA. The effect of this deficiency on subsequent cognitive development is not well understood. ...

        Research

        Early Years and Disadvantage: Matching Developmental Circumstances in Populations to Prevention and Intervention Opportunities

        In this chapter we use rich longitudinal data to examine the typical growth of vocabulary in children as they age from 4 years onwards. ...

        Research

        Chemotherapy-induced peripheral neuropathy in children and adolescent cancer patients

        Brain cancer and leukemia are the most common cancers diagnosed in the pediatric population and are often treated with lifesaving chemotherapy. However, chemotherapy causes severe adverse effects and chemotherapy-induced peripheral neuropathy (CIPN) is a major dose-limiting and debilitating side effect. ...

        Research

        Can telehealth increase physical activity in individuals with Rett syndrome? A multicentre randomized controlled trial

        To evaluate the effects of a physical activity programme on sedentary behaviour and physical activity in ambulant individuals with Rett syndrome. ...

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