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        Comparative assessment of the human and animal health surveillance systems in Tanzania: Opportunities for an integrated one health surveillance platform

        Globally, there have been calls for an integrated zoonotic disease surveillance system. This study aimed to assess human and animal health surveillance systems to identify opportunities for One Health surveillance platform in Tanzania. ...

        Research

        The immunogenetic impact of European colonization in the Americas

        The introduction of pathogens originating from Eurasia into the Americas during early European contact has been associated with high mortality rates among Indigenous peoples, likely contributing to their historical and precipitous population decline. ...

        Research

        Equity, diversity, and inclusion at the Global Alliance for Genomics and Health

        A lack of diversity in genomics for health continues to hinder equitable leadership and access to precision medicine approaches for underrepresented populations. To avoid perpetuating biases within the genomics workforce and genomic data collection practices, equity, diversity, and inclusion (EDI) must be addressed. ...

        Research

        Glucose enhancement of human memory:

        The brain relies upon glucose as its primary fuel. In recent years, a rich literature has developed from both human and animal studies indicating... ...

        Research

        Individuals with Inflammatory Bowel Disease Have an Altered Gut Microbiome Composition of Fungi and Protozoa

        It is known that the bacterial gut microbiome is altered in inflammatory bowel disease (IBD), but far less is known about the role of eukaryotic microorganisms in IBD. ...

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        Freya Shearer

        Honorary Research Associate ...

        Research

        Intrauterine growth restriction predisposes to airway inflammation without disruption of epithelial integrity in postnatal male mice

        Evidence from animal models demonstrate that intrauterine growth restriction (IUGR) alters airway structure and function which may affect susceptibility to disease. Airway inflammation and dysregulated epithelial barrier properties are features of asthma which have not been examined in the context of IUGR. ...

        Research

        Investigations into the role of ST2 in acute asthma in children

        This study investigated the potential role of ST2 in children with acute asthma. ...

        Research

        Developmental vitamin D deficiency produces behavioral phenotypes of relevance to Autism in an animal model

        Here we investigate these features in an animal model related to autism spectrum disorder - the DVD-deficient rat ...

        Research

        Allelic bias when performing in-solution enrichment of ancient human DNA

        In-solution hybridisation enrichment of genetic variation is a valuable methodology in human paleogenomics. It allows enrichment of endogenous DNA by targeting genetic markers that are comparable between sequencing libraries. Many studies have used the 1240k reagent-which enriches 1,237,207 genome-wide SNPs-since 2015, though access was restricted. ...

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