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        Research

        School Readiness of Children Exposed to Family and Domestic Violence

        Children have a universal right to live free from exposure to family and domestic violence (FDV). Children exposed to FDV can experience long-term effects on their physical and psychological health and their social competencies including social, emotional, and cognitive skills and behaviours that underpin successful social adaptation and academic achievement. The aim of this study was to investigate if children exposed to FDV were more likely to be vulnerable on school readiness measures compared to those children who were not exposed. ...

        Research

        Using Linked Population Data to Investigate the Impact of Intimate Partner Violence on Children's Outcomes

        Melissa Rebecca O'Donnell Glauert M RA BPsych (Hons), MPsych, GradDip Ed, PhD BPsych (Hons) PhD Honorary Research Associate Honorary Research ...

        Research

        Immunoinflammatory responses to febrile lower respiratory infections in infants display uniquely complex/intense transcriptomic profiles

        the association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories ...

        Research

        Asthma and allergies in a cohort of adolescents conceived with ART

        Research question: Are asthma and allergies more common in adolescents conceived with assisted reproductive technologies (ART) compared with adolescents conceived without? ...

        Research

        Remission of peanut allergy is associated with rewiring of allergen-driven T helper 2-related gene networks

        The immunological changes underpinning acquisition of remission (also called sustained unresponsiveness) following food immunotherapy remain poorly defined. Limited access to effective therapies and biosamples from treatment responders has prevented progress. Probiotic peanut oral immunotherapy is highly effective at inducing remission, providing an opportunity to investigate immune changes. ...

        Pregnancy and Early Life Immunology

        The Pregnancy and Early Life Immunology team's overall research vision is targeted towards understanding immunological development during early life. ...

        Research

        Sex-Specific Environmental Impacts on Initiation and Progression of Multiple Sclerosis

        The immunological mechanisms that contribute to multiple sclerosis (MS) differ between males and females. Females are 2-3 times more likely to develop MS compared to males, however the reason for this discrepancy is unknown. Once MS is established, there is a more inflammatory yet milder form of disease in females whereas males generally suffer from more severe disease and faster progression, neural degradation, and disability. ...

        Research

        Bullying and psychosocial adjustment among children with and without asthma

        Children with asthma face serious mental health risk, but the pathways remain unclear. This study aimed to examine bullying victimisation and perpetration in children with asthma and a comparison sample without a chronic health condition, and the role of bullying in moderating psychosocial adjustment outcomes for those with asthma. A sample of children with and without asthma, and their parents, were recruited from hospital clinics. ...

        Research

        Assessing neutrophil subsets in autoimmune disease: Moving away from relying on density?

        Neutrophils are the most abundant immune cell in circulation. However, due to a number of technical challenges for researchers, including the neutrophil's short lifespan and difficulties with preservation, they are often discarded during blood processing and thus ignored in cohort studies. As such, the contribution of neutrophils to disease and their involvement in disease mechanisms is less explored compared with other immune cell types. ...

        Research

        Geographical migration and fitness dynamics of Streptococcus pneumoniae

        Streptococcus pneumoniae is a leading cause of pneumonia and meningitis worldwide. Many different serotypes co-circulate endemically in any one location. The extent and mechanisms of spread and vaccine-driven changes in fitness and antimicrobial resistance remain largely unquantified. ...

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