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        Research

        Progress in Model Systems of Cystic Fibrosis Mucosal Inflammation to Understand Aberrant Neutrophil Activity

        Here we examine the latest findings of neutrophils in pediatric CF lung disease and proposed mechanisms of their pathogenicity ...

        Research

        A comparative study of extracellular vesicle-associated and cell-free DNA and RNA for HPV detection in oropharyngeal squamous cell carcinoma

        Our study demonstrates that although HPV-DNA/RNA can be detected in EV associated DNA/RNA, cf-DNA/RNA is the more sensitive liquid biopsy medium ...

        Research

        Longitudinal Analysis of Group A Streptococcus emm Types and emm Clusters in a High-Prevalence Setting: Relationship between Past and Future Infections

        No evidence of tissue tropism was observed, and there was no apparent selective pressure or constraint of emm types ...

        Research

        Effects of serotonin depletion and dopamine depletion on bimodal divided attention

        The results indicate a possible dissociation between the effects of a diminished brain 5-HT and DA synthesis on the performance in a bimodal divided attention task ...

        Research

        Spotting sporotrichosis skin infection: The first Australian paediatric case series

        These data highlight the importance of recognising Sporotrichosis in children outside an outbreak setting ...

        Research

        Oestrogen amplifies pre-existing atopy-associated Th2 bias in an experimental asthma model

        The role of oestrogen in experimental atopic asthma, and guide future research on sex-related variations in atopic asthma susceptibility/intensity ...

        Research

        Simultaneous Targeting of DNA Replication and Homologous Recombination in Glioblastoma with a Polyether Ionophore

        Our findings highlight the potential of salinomycin to induce DNA lesions and inhibit homologous recombination to greatly enhance the effect of radiotherapy ...

        Research

        The impact of new universal child influenza programs in Australia: Vaccine coverage, effectiveness and disease epidemiology in hospitalised children in 2018

        A significant reduction in severe influenza was observed in Australian children, possibly contributed to by improved vaccine coverage and high vaccine effectiveness ...

        Research

        Lessons learned in genetic research with Indigenous Australian participants

        We reflect on the lessons learned from a recent genome‐wide association study of rheumatic heart disease with Aboriginal Australian participants ...

        Research

        Low-dose UV radiation before running wheel access activates brown adipose tissue

        When combined with physical activity, low-dose UVR may more effectively limit adiposity and modulate metabolic and immune pathways in iBAT ...

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