In Australia, community playgroups are seen as the ‘soft touch’. But a research project in Tonga is finding the benefits can last a lifetime. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2017
• July

We believe this data represents a useful resource to understand the central nervous system in macaque. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• March 2017

The aims of the present study were to (i) examine the relationship between children's degree of adiposity and psychosocial functioning; and (ii) compare patterns of clustering of psychosocial measures between healthy weight and overweight/obese children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2008
• February 2008

Advances in gene and molecular technology finally explain why brain tumour cells that look the same, behave and respond differently to treatment. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2014
• March

A systematic review of current evidence using various electronic databases was conducted. Studies were appraised using a recognised clinical appraisal tool. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• March 2018

The pattern of association between socioeconomic factors and health outcomes has primarily depicted better health for those who are higher in the social... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• November 2011

Progress in psychiatric genetics has been slow despite evidence of high heritability for most mental disorders ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

Rishi Sury Laurence Sébastien Kotecha Cheung Malinge RS LC SM MB ChB (Hons) MRCPCH FRACP PhD BPharm (Hons) MBA PhD PhD Co-Head, Leukaemia ...

• 1. Telethon Kids Institute
• Projects

Rearrangements of the Mixed Lineage Leukemia (MLL/KMT2A) gene are present in approximately 10% of acute leukemias and characteristically define disease with poor outcome. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

Cancer cells display DNA hypermethylation at specific CpG islands in comparison to their normal healthy counterparts, but the mechanism that drives this so-called CpG island methylator phenotype (CIMP) remains poorly understood. Here, we show that CpG island methylation in human T-cell acute lymphoblastic leukemia (T-ALL) mainly occurs at promoters of Polycomb Repressor Complex 2 (PRC2) target genes that are not expressed in normal or malignant T-cells and which display a reciprocal association with H3K27me3 binding. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• November 2020