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        Research

        Reference exome data for Australian Aboriginal populations to support health-based research

        Our data set provides a useful reference point for genomic studies on Aboriginal Australians ...

        Research

        Clinical Management of Staphylococcus aureus Bacteremia in Neonates, Children, and Adolescents

        Staphylococcus aureus is a common cause of community and health care-associated bacteremia, with authors of recent studies estimating the incidence of S aureus bacteremia (SAB) in high-income countries between 8 and 26 per 100 000 children per year. Despite this, <300 children worldwide have ever been randomly assigned into clinical trials to assess the efficacy of treatment of SAB. ...

        Research

        Children's neighbourhood physical environment and early development: an individual child level linked data study

        The neighbourhood physical environment has a weak but significant association with early childhood development ...

        Research

        Clinical protocol for a longitudinal cohort study to identify markers of vaccine immunogenicity in newborn infants in the gambia and papua New Guinea

        Immunity is distinct in early life and greater precision is required in our understanding of mechanisms of early life protection to inform development of new pediatric vaccines ...

        Research

        Associations between clusters of early life risk factors and developmental vulnerability at age 5

        This study investigated the associations between clusters of early life risk factors and developmental vulnerability in children's first year of full-time school at age 5 ...

        Research

        Diverse Anti-Tumor Immune Potential Driven by Individual IFNα Subtypes

        Our data shows that the expression of distinct IFNα subtypes within the tumor microenvironment results in different anti-tumor activities ...

        Research

        Progress in Model Systems of Cystic Fibrosis Mucosal Inflammation to Understand Aberrant Neutrophil Activity

        Here we examine the latest findings of neutrophils in pediatric CF lung disease and proposed mechanisms of their pathogenicity ...

        Research

        A comparative study of extracellular vesicle-associated and cell-free DNA and RNA for HPV detection in oropharyngeal squamous cell carcinoma

        Our study demonstrates that although HPV-DNA/RNA can be detected in EV associated DNA/RNA, cf-DNA/RNA is the more sensitive liquid biopsy medium ...

        Research

        Effects of serotonin depletion and dopamine depletion on bimodal divided attention

        The results indicate a possible dissociation between the effects of a diminished brain 5-HT and DA synthesis on the performance in a bimodal divided attention task ...

        Research

        Longitudinal Analysis of Group A Streptococcus emm Types and emm Clusters in a High-Prevalence Setting: Relationship between Past and Future Infections

        No evidence of tissue tropism was observed, and there was no apparent selective pressure or constraint of emm types ...

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