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        Research

        Systematic analysis of transcription start sites in avian development

        CAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell populations. ...

        Research

        Analysis of the human monocyte-derived macrophage transcriptome and response to lipopolysaccharide provides new insights into genetic aetiology of inflammatory bowel disease.

        We propose that this system provides a model for the differentiation and adaptation of monocytes entering the intestinal lamina propria. ...

        Research

        Invasive fungal disease in children with solid tumors: An Australian multicenter 10-year review

        Invasive fungal disease (IFD) occurs less frequently during treatment for solid compared to hematological malignancies in children, and risk groups are poorly defined. Retrospective national multicenter cohort data (2004-2013) were analyzed to document prevalence, clinical characteristics, and microbiology of IFD. ...

        Research

        Effectiveness of seasonal trivalent influenza vaccination against hospital-attended acute respiratory infections in pregnant women

        Influenza vaccination during pregnancy was associated with significantly fewer hospital attendances for ARI in pregnant women ...

        News & Events

        Looking at autism through a social model

        In​ this blog, Speech Pathologist Linda Arabi discusses the social model and how it influences the supports we provide to autistic children and their families. ...

        News & Events

        Tribute to Dr Clyde Hertzman

        Researchers at Perth's Telethon Institute for Child Health Research are mourning the sudden passing of Canadian child development expert Dr Clyde Hertzman ...

        News & Events

        Skin infections send eight out of every 100 Aboriginal babies to hospital

        In a WA first, researchers from Telethon Kids Institute have shown that Aboriginal babies are 22.5 times more likely to be treated for skin infections than non-Aboriginal babies. ...

        Research

        Functional validation of variants of unknown significance using CRISPR gene editing and transcriptomics: A Kleefstra syndrome case study

        There are an estimated > 400 million people living with a rare disease globally, with genetic variants the cause of approximately 80% of cases. Next Generation Sequencing (NGS) rapidly identifies genetic variants however they are often of unknown significance. ...

        Research

        Influenza C infections in Western Australia and Victoria from 2008 to 2014

        Comparison of Influenza C viruses detected from Australian clinical samples with Influenza C viruses detected in other parts of the world in recent years ...

        Research

        The interplay between sarcoma and surgery-induced wound healing

        Timo W. Joost Lassmann Lesterhuis T WJL BSc (Hons) MSc PhD Feilman Fellow; Program Head, Precision Health and Team Lead, Computational Biology ...

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