Elucidation of early life factors is critical to understand the development of allergic diseases, especially those manifesting in early life such as food allerg ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• November 2010

Initial findings suggest the potential of the instrument in helping identifying positive veteran teachers within systems, as well as the voracity of the research approach ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019

This review focuses primarily on the beneficial effects for human health of exposure to ultraviolet radiation ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

Here we report that CHAF1B is required for normal hematopoiesis while its overexpression promotes leukemia ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• November 2018

Prospective birth cohort studies tracking asthma initiation and consolidation in community cohorts have identified viral infections occurring against a... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• May 2012

In this study of healthy adults aged 50-85 and 18-24 years, SA3Ag elicited a rapid and robust immune response and was well tolerated, with no notable safety... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• February 2015

Terrance W. Joost Ben Johns Lesterhuis Wylie T WJL BW BSc PhD Honorary Research Associate Program Head, Cancer; Chronic and Severe Diseases RFA ...

• 1. Telethon Kids Institute
• Projects

Maternal diet during pregnancy has long been recognised as an important determinant of neonatal outcomes and child development. Infant body composition is a potentially modifiable risk factor for predicting future health and metabolic disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022

B cells are critical to the development of multiple sclerosis (MS), but the mechanisms by which they contribute to the disease are poorly defined. We hypothesised that the expression of CD32b (FcγRIIb), a receptor for the Fc region of IgG with inhibitory activities in B cells, is lower on B cell subsets from people with clinically isolated syndrome (CIS) or MS. CD32b expression was highest on post-naive IgM+ B cell subsets in healthy controls. For females with MS or CIS, significantly lower CD32b expression was identified on IgM+ B cell subsets, including naive and IgMhi MZ-like B cells, when compared with control females. Lower CD32b expression on these B cell subsets was associated with detectable anti-Epstein Barr Virus viral capsid antigen IgM antibodies, and higher serum levels of B cell activating factor. To investigate the effects of lower CD32b expression, B cells were polyclonally activated in the presence of IgG immune complexes, with or without a CD32b blocking antibody, and the expression of TNF and IL-10 in B cell subsets was assessed. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• January 2021

Researchers at the Telethon Kids Institute have found children with vitamin D deficiency are more likely to develop asthma. ...

• 1. Telethon Kids Institute
• News & Events
• News & Events at Telethon Kids
• 2016
• November