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        Research

        Infection is the major component of the disease burden in Aboriginal and non-Aboriginal Australian children: a population-based study

        Infection accounts for the majority of pediatric mortality and morbidity in developing countries, but there are limited data on the infectious diseases... ...

        Research

        Defining the pediatric response to SARS-CoV-2 variants

        The global population has been severely affected by the coronavirus disease 2019 (COVID-19) pandemic, however, with older age identified as a risk factor, children have been underprioritized. This article discusses the factors contributing to the less severe response observed in children following infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including, differing viral entry receptor expression and immune responses. ...

        Research

        Invasive fungal disease in children with solid tumors: An Australian multicenter 10-year review

        Invasive fungal disease (IFD) occurs less frequently during treatment for solid compared to hematological malignancies in children, and risk groups are poorly defined. Retrospective national multicenter cohort data (2004-2013) were analyzed to document prevalence, clinical characteristics, and microbiology of IFD. ...

        Research

        Epidemiology and assessment of Hepatitis B positive children in Western Australia

        To describe the characteristics of patients with chronic hepatitis B (CHB) presenting to a tertiary paediatric hospital in Perth, Western Australia. Review of implementation of previous follow-up recommendations for the cohort was also undertaken.  ...

        Research

        Randomised controlled trials of behavioural nudges delivered through text messages to increase influenza and COVID-19 vaccines among pregnant women (the EPIC study): study protocol

        Influenza and COVID-19 infections during pregnancy may have serious adverse consequences for women as well as their infants. However, uptake of influenza and COVID-19 vaccines during pregnancy remains suboptimal. This study aims to assess the effectiveness of a multi-component nudge intervention to improve influenza and COVID-19 vaccine uptake among pregnant women.  ...

        Research

        Changing rules, recommendations, and risks: COVID-19 vaccination decisions and emotions during pregnancy

        As COVID-19 vaccinations rolled out globally from late 2020, rules and recommendations regarding vaccine use in pregnancy shifted rapidly. Pre-registration COVID-19 vaccine trials excluded those who were pregnant. Initial Australian medical advice did not routinely recommend COVID-19 vaccines in pregnancy, due to limited safety data and little perceived risk of local transmission. ...

        Research

        Effectiveness of seasonal trivalent influenza vaccination against hospital-attended acute respiratory infections in pregnant women

        Influenza vaccination during pregnancy was associated with significantly fewer hospital attendances for ARI in pregnant women ...

        Research

        Immunisation and pregnancy - who, what, when and why?

        Recommending vaccination to pregnant women is important as evidence shows they are more likely to get vaccinated if their healthcare provider advises it ...

        Research

        Modelling the seasonal epidemics of respiratory syncytial virus in young children

        This paper describes a mathematical model used to predict when an epidemic of respiratory syncytial virus (RSV) will occur so that preventive measures, such... ...

        Research

        FluBubs: Safety and immunogenicity of Early Quadrivalent Influenza Vaccine

        Christopher Tobias Blyth Kollmann CC TK MBBS (Hons) DCH FRACP FRCPA PhD PhD, M.D., SFUW Director, Wesfarmers Centre of Vaccines and Infectious ...

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