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        221-230 of 1006 results for 'cancer'

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        Research

        From signalling pathways to targeted therapies: unravelling glioblastoma’s secrets and harnessing two decades of progress

        Glioblastoma, a rare, and highly lethal form of brain cancer, poses significant challenges in terms of therapeutic resistance, and poor survival rates for both adult and paediatric patients alike. Despite advancements in brain cancer research driven by a technological revolution, translating our understanding of glioblastoma pathogenesis into improved clinical outcomes remains a critical unmet need. ...

        Research

        Incidence and survival for childhood central nervous system tumours in Australia, 1983–2016

        To investigate incidence and survival of childhood tumours of the central nervous system (CNS) by histological subtype, tumour behaviour and tumour grade. Methods: National, population-based data on all children under 15 years old diagnosed with a CNS tumour between 1983 and 2016 were sourced from the Australian Childhood Cancer Registry. Incidence rate trends were calculated using Joinpoint regression. ...

        News & Events

        Funding boost to melanoma research

        A Telethon Kids Institute researcher will investigate new ways to harness the body’s own immune system to fight melanoma, thanks to Cancer Council WA funding. ...

        Research

        SNAIL trail in myeloid malignancies

        Transcription factors known to induce the epithelial-to-mesenchymal transition (EMT) (such as ZEB1/2 [zinc finger E-box binding homeobox 1/2], SNAI1/2/3, and TWIST1/2) have been undoubtedly implicated in tumorigenesis, cancer progression, metastasis, and chemoresistance in solid tumors; however, their role in normal and malignant hematopoiesis has been underappreciated for many years. ...

        Research

        SunSmart messaging for WA young people

        Robyn Johnston RJ BSc, Post Grad Dip, PhD Senior Research Officer robyn.johnston@telethonkids.org.au Senior Research Officer Robyn Johnston is a ...

        Research

        Potassium Ion Channels in Malignant Central Nervous System Cancers

        Malignant central nervous system (CNS) cancers are among the most difficult to treat, with low rates of survival and a high likelihood of recurrence. This is primarily due to their location within the CNS, hindering adequate drug delivery and tumour access via surgery. Furthermore, CNS cancer cells are highly plastic, an adaptive property that enables them to bypass targeted treatment strategies and develop drug resistance. ...

        Research

        Silencing of TESTIN by dense biallelic promoter methylation

        Aberrant promoter DNA methylation has been reported in childhood acute lymphoblastic leukaemia and has the potential to contribute to its onset and outcome ...

        News & Events

        New childhood brain tumour drugs to be tested

        It is the kids he treats in his role as a paediatric oncologist that motivate Dr Nick Gottardo in his work as a Telethon Kids Institute cancer researcher. ...

        News & Events

        Farewelling Jette Ford – a Telethon Kids legend

        The Telethon Kids Institute has farewelled one of its most treasured employees, with research officer Jette Ford closing the door on a quietly stellar 37-year career which has changed the face of cancer research in WA and around the world. ...

        Research

        Challenges to curing primary brain tumours

        The seven key challenges summarized in this Position Paper are intended to serve as foci for future research and investment in brain tumours ...

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