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        Research

        The effect of azithromycin on structural lung disease in infants with cystic fibrosis (COMBAT CF): a phase 3, randomised, double-blind, placebo-controlled clinical trial

        Structural lung disease and neutrophil-dominated airway inflammation is present from 3 months of age in children diagnosed with cystic fibrosis after newborn screening. We hypothesised that azithromycin, given three times weekly to infants with cystic fibrosis from diagnosis until age 36 months, would reduce the extent of structural lung disease as captured on chest CT scans. ...

        Research

        Fetal alcohol spectrum disorder: the importance of assessment, diagnosis and support in the Australian justice context

        The current article outlines how individuals with fetal alcohol spectrum disorder may experience inequities within the justice system ...

        Research

        Prevalence of tracheobronchomalacia is higher than previously reported in children with cystic fibrosis

        Tracheobronchomalacia (TBM) is estimated to be present in 1 in 2100 children. Previous reports suggest the prevalence is higher in children with cystic fibrosis (CF). This has clinical implications with potential to influence airway clearance and lung health. ...

        Research

        Standardised treatment and monitoring protocol to assess safety and tolerability of bacteriophage therapy for adult and paediatric patients (STAMP study): protocol for an open-label, single-arm trial

        There has been renewed interest in the therapeutic use of bacteriophages (phages); however, standardised therapeutic protocols are lacking, and there is a paucity of rigorous clinical trial data assessing efficacy. ...

        Research

        Randomised controlled trials in cystic fibrosis: What, when and how?

        The major morbidity and mortality from cystic fibrosis (CF) comes from progressive lung disease with bronchiectasis leading to respiratory failure ...

        Research

        Improving disease surveillance data analysis, interpretation, and use at the district level in Tanzania

        An effective disease surveillance system is critical for early detection and response to disease epidemics. This study aimed to assess the capacity to manage and utilize disease surveillance data and implement an intervention to improve data analysis and use at the district level in Tanzania. ...

        News & Events

        Research roundup

        Take a look at some of the published research to come out of the Children's Diabetes Centre recently. ...

        News & Events

        Diabetes distress and teens

        During National Diabetes Week, we take a look at diabetes distress and what research the Children's Diabetes Centre is doing to improve the mental health and wellbeing of young people with diabetes and their families. ...

        Research

        Defective function at the epithelial junction: A novel therapeutic frontier in asthma?

        The airway epithelium forms a highly regulated physical barrier that normally prevents invasion of inhaled pathogens and allergens from the airway lumen. ...

        Postdoctoral Research Fellow - Autism Research

        The Autism Research Team at the Telethon Kids Institute is seeking applications from enthusiastic and ambitious early-career researchers for the ...

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